Abstract：
Flavonoids or phenolic compounds are part of the daily intake of every human being. Though they are positive traders for metabolism, excessive intakes bring about detrimental impacts on human health. Herein, the anti-cancer capacitive nature quercetin (Qc) was electrochemically detected through the rare earth metal-based sphere like praseodymium vanadate (PrVO4) entrapped graphitic carbon nitride (g-CN) as electrode modifiers. The nanocomposite was prepared by the one-pot hydrothermal method and characterized by phase compositional and morphology-based techniques. The existing synergistic nature between the PrV@g-CN (praseodymium vanadate@graphitic carbon nitride) makes them have an enhanced electrochemical response towards the Qc than the individual material. The obtained cyclic voltammogram and differential pulse voltammogram profile show one major oxidation peak which is attributed to the conversion of quercetin to quercetin-o-quinone. The PrV@g-CN/GCE (GCE- glassy carbon electrode) shows a good electrochemical active surface area (A = 110 cm2) and linear range between 0.05 and 252.00 μM with a LOD (limit of detection) of 0.002 µM. Moreover, the PrV@g-CN/GCE exhibits good current retention (94.76 %) around 14 days and appreciable repeatability (RSD- 0.5 %) and reproducibility (RSD- 1.3 %) towards the Qc. The real-time implementation of the proposed sensor exhibits a good recovery range towards the black tea (95.00-98.10 %) and green tea (97.80-99.60 %).
摘要：
类黄酮或酚类化合物是每个人每日摄入的一部分。虽然他们是新陈代谢的积极交易者，过量摄入会对人类健康产生有害影响。在这里，抗癌电容性质槲皮素（Qc）是通过基于稀土金属的球体，如钒酸镨（PrVO4）包埋的石墨氮化碳（g-CN）作为电极改性剂进行电化学检测的。纳米复合材料是通过一锅法水热法制备的，并通过基于相组成和形态的技术进行了表征。PrV@g-CN(钒酸镨@石墨碳氮化物)之间存在的协同性质使得它们比单个材料具有增强的对Qc的电化学响应。获得的循环伏安图和差分脉冲伏安图曲线显示了一个主要的氧化峰，这归因于槲皮素向槲皮素-邻醌的转化。PrV@g-CN/GCE（GCE-玻碳电极）显示出良好的电化学活性表面积（A=110cm2），线性范围在0.05至252.00μM之间，LOD（检测限）为0.002µM。此外，PrV@g-CN/GCE在14天左右表现出良好的电流保留率（94.76％），以及对Qc的可重复性（RSD-0.5％）和可重复性（RSD-1.3％）。所提出的传感器的实时实现对红茶（95.00-98.10％）和绿茶（97.80-99.60％）具有良好的恢复范围。
