Abstract：
BACKGROUND: Problematic use of mobile phones (PMPU) has been described as a serious public health issue.
METHODS: This study was a parallel three-arm randomized controlled trial and has completed registration (ClinicalTrials.gov Identifier: NCT05843591). Ninety college students with PMPU were randomly assigned to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or the wait-list control group (WLC group, n = 30). At the end of the intervention, stool samples from the study participants were collected for biological analysis based on 16 S rDNA amplicon sequencing technology. The primary outcome was addiction symptoms assessed by the Smartphone Addiction Scale-Short Version (SAS-SV). The secondary outcomes are emotional symptoms, physical symptoms, and flora species.
RESULTS: Compared with the WLC group, the AE and TCC groups showed reductions in PMPU levels, physical and mental fatigue, but there was no difference between the two groups. Moreover, the effect of increasing self-esteem embodied in the TCC group was not present in the AE group. Compared to the WLC group, the relative abundance of Bacteroidaceae and Bacteroides were lower in the AE group, while the relative abundance of Erysipelotrichaceae and Alistipes were lower in the TCC group. And the relative abundance of Bacteroidaceae, Bacteroides, and Alistipes were significantly and negatively correlated with the decline in PMPU scores.
CONCLUSIONS: AE or TCC is an effective, safe and efficient intervention for college students with PMPU, providing some physiological and psychological benefits and having some impact on their intestinal flora.
METHODS: This study was a parallel three-arm randomized controlled trial and has completed registration (ClinicalTrials.gov Identifier: NCT05843591). Ninety college students with PMPU were randomly assigned to the aerobic exercise group (AE group, n = 30), the Tai Chi Chuan group (TCC group, n = 30), or the wait-list control group (WLC group, n = 30). At the end of the intervention, stool samples from the study participants were collected for biological analysis based on 16 S rDNA amplicon sequencing technology. The primary outcome was addiction symptoms assessed by the Smartphone Addiction Scale-Short Version (SAS-SV). The secondary outcomes are emotional symptoms, physical symptoms, and flora species.
RESULTS: Compared with the WLC group, the AE and TCC groups showed reductions in PMPU levels, physical and mental fatigue, but there was no difference between the two groups. Moreover, the effect of increasing self-esteem embodied in the TCC group was not present in the AE group. Compared to the WLC group, the relative abundance of Bacteroidaceae and Bacteroides were lower in the AE group, while the relative abundance of Erysipelotrichaceae and Alistipes were lower in the TCC group. And the relative abundance of Bacteroidaceae, Bacteroides, and Alistipes were significantly and negatively correlated with the decline in PMPU scores.
CONCLUSIONS: AE or TCC is an effective, safe and efficient intervention for college students with PMPU, providing some physiological and psychological benefits and having some impact on their intestinal flora.
摘要：
背景：移动电话（PMPU）的问题使用已被描述为严重的公共卫生问题。
方法：本研究是一项平行的三臂随机对照试验，已完成注册（ClinicalTrials.govIdentifier：NCT05843591）。将90名PMPU大学生随机分为有氧运动组(AE组,n=30),太极拳小组(TCC小组，n=30),或等待列表控制组（WLC组，n=30)。在干预结束时,根据16SrDNA扩增子测序技术,收集研究参与者的粪便样本进行生物学分析.主要结果是通过智能手机成瘾量表简版（SAS-SV）评估的成瘾症状。次要结果是情绪症状，身体症状,和植物物种。
结果：与WLC组相比，AE和TCC组显示PMPU水平降低，身心疲劳,但是两组之间没有差异。此外，TCC组的自尊心增加的影响在AE组中不存在。与WLC组相比，AE组中拟杆菌科和拟杆菌的相对丰度较低，而在TCC组中，Erypelotricaceae和Alistipes的相对丰度较低。以及拟杆菌科的相对丰度，拟杆菌,和Alistipes与PMPU评分的下降呈显著负相关。
结论：AE或TCC是有效的，对PMPU大学生进行安全有效的干预，提供一些生理和心理益处，并对他们的肠道菌群产生一些影响。
方法：本研究是一项平行的三臂随机对照试验，已完成注册（ClinicalTrials.govIdentifier：NCT05843591）。将90名PMPU大学生随机分为有氧运动组(AE组,n=30),太极拳小组(TCC小组，n=30),或等待列表控制组（WLC组，n=30)。在干预结束时,根据16SrDNA扩增子测序技术,收集研究参与者的粪便样本进行生物学分析.主要结果是通过智能手机成瘾量表简版（SAS-SV）评估的成瘾症状。次要结果是情绪症状，身体症状,和植物物种。
结果：与WLC组相比，AE和TCC组显示PMPU水平降低，身心疲劳,但是两组之间没有差异。此外，TCC组的自尊心增加的影响在AE组中不存在。与WLC组相比，AE组中拟杆菌科和拟杆菌的相对丰度较低，而在TCC组中，Erypelotricaceae和Alistipes的相对丰度较低。以及拟杆菌科的相对丰度，拟杆菌,和Alistipes与PMPU评分的下降呈显著负相关。
结论：AE或TCC是有效的，对PMPU大学生进行安全有效的干预，提供一些生理和心理益处，并对他们的肠道菌群产生一些影响。
