NLRP1 和氧化的 TRX1 之间的相互作用涉及瞬时二硫键。
关键词: AlphaFold-Multimer NLRP1 disulfide inflammasome pyroptosis redox thioredoxin
Mesh : Humans Oxidation-Reduction Disulfides / chemistry metabolism Thioredoxins / metabolism chemistry NLR Proteins / metabolism chemistry Adaptor Proteins, Signal Transducing / metabolism chemistry HEK293 Cells Apoptosis Regulatory Proteins / metabolism chemistry Inflammasomes / metabolism Cysteine / metabolism chemistry
来 源:
DOI:10.1016/j.chembiol.2023.12.012
PDF(Pubmed)