PDF(Pubmed)
Abstract：
There is a growing demand and use of herbal cosmetics for skin purposes due to their perceived safety when applied to the skin. Three Cassipourea species commonly known as \"ummemezi\" are used interchangeably by women in rural areas of Eastern Cape and KwaZulu-Natal provinces to treat hypermelanosis as well as sun protection. We conducted a phytochemical comparison of three Cassipourea species; Cassipourea flanaganii (Schinz) Alston, Cassipourea gummiflua Tul. verticillata (N.E.Br.) J. Lewis and Cassipourea malosana (Baker) Alston by Liquid Chromatography-Mass Spectrometry (LC-MS/MS) analysis in negative mode. The results obtained from the LC-MS/MS yielded a total number of twenty-four compounds of different chemical classes, including fatty acids, steroids, di- and tri-terpenoids, flavonoids, phenolic acids, and eighteen among them were tentatively identified. The LC-MS /MS analysis showed that the three studied Cassipourea extracts contain compounds that have anti-tyrosinase activity and consequently. The presence of these compounds, either in synergy or individually, can be attributed to the anti-tyrosinase effect. Although the traditional names of the species are used interchangeably, they are different, however, they possess similar skin-lightening properties. Despite the recent popularity of modern cosmetic products, plants continue to play an important role in the local cosmetics industry in South Africa\'s Eastern Cape and KwaZulu-Natal community provinces.
摘要：
用于皮肤目的的草药化妆品的需求和使用日益增长,这是由于它们在施用于皮肤时感知到的安全性。东开普省和夸祖鲁-纳塔尔省农村地区的妇女可以互换使用三种通常被称为“ummemeezi”的Cassipourea物种来治疗黑色素沉着症和防晒。我们对三种Cassipourea物种进行了植物化学比较；Cassipoureaflanaganii（Schinz）Alston，卡西波拉胶布图。Verticillata(N.E.Br.）J.Lewis和Cassipoureamalosana（Baker）Alston通过液相色谱-质谱（LC-MS/MS）分析在负模式下。从LC-MS/MS获得的结果产生了总共24种不同化学类别的化合物，包括脂肪酸,类固醇,二萜类和三萜类，黄酮类化合物，酚酸，其中18人被初步确定。LC-MS/MS分析显示,所研究的三种仙草提取物含有具有抗酪氨酸酶活性并因此具有抗酪氨酸酶活性的化合物。这些化合物的存在，无论是协同作用还是单独作用，可归因于抗酪氨酸酶作用。尽管该物种的传统名称可以互换使用，他们是不同的，然而,它们具有相似的皮肤美白特性。尽管现代化妆品最近很受欢迎，植物继续在南非东开普省和夸祖鲁-纳塔尔省的当地化妆品行业发挥重要作用。
