PDF(Pubmed)
Abstract：
BACKGROUND: The TsiogkaSpaeth (TS) grid is a new, low-cost, and easy to access portable test for visual field (VF) screening which could be used by clinicians in everyday clinical practice. Our study aimed to determine the validity of an innovative screening grid test for identifying neurological disease-associated VF defects.
METHODS: We enrolled two groups of participants: We assessed the one eye of ten consecutive adult patients with different types of neurological disease associated VF defects and ten eyes of controls in each group. The TS grid test was performed in each group. Sensitivity, specificity, and positive and negative predictive values of the TS grid scotoma area were assessed using the 24-2 VF Humphrey field analyzer (HFA) as the reference standard.
RESULTS: Sensitivity and specificity of the TS grid test were 100% and 90.91%, respectively. The area under curve was 0.9545 with 95% CI 0.87-1.00. There was a significant correlation between the number of missed locations on the TS grid test and the visual field index of the HFA 24-2 (r = 0.9436, P < .0001).
CONCLUSIONS: The sensitivity and specificity of the TS grid test were high in detecting VF defects in neurological disease. The TS grid test appears to be a reliable, low-cost, and easily accessed alternative to traditional VF tests in diagnosing typical neurological patterns of visual field defects. It would be useful in screening subjects for neurologically derived ocular morbidity in everyday clinical practice and in remote areas deprived of specialized health care services.
METHODS: We enrolled two groups of participants: We assessed the one eye of ten consecutive adult patients with different types of neurological disease associated VF defects and ten eyes of controls in each group. The TS grid test was performed in each group. Sensitivity, specificity, and positive and negative predictive values of the TS grid scotoma area were assessed using the 24-2 VF Humphrey field analyzer (HFA) as the reference standard.
RESULTS: Sensitivity and specificity of the TS grid test were 100% and 90.91%, respectively. The area under curve was 0.9545 with 95% CI 0.87-1.00. There was a significant correlation between the number of missed locations on the TS grid test and the visual field index of the HFA 24-2 (r = 0.9436, P < .0001).
CONCLUSIONS: The sensitivity and specificity of the TS grid test were high in detecting VF defects in neurological disease. The TS grid test appears to be a reliable, low-cost, and easily accessed alternative to traditional VF tests in diagnosing typical neurological patterns of visual field defects. It would be useful in screening subjects for neurologically derived ocular morbidity in everyday clinical practice and in remote areas deprived of specialized health care services.
摘要：
背景：TsiogkaSpaeth（TS）网格是一种新的，低成本,并且易于访问用于视野（VF）筛查的便携式测试，可供临床医生在日常临床实践中使用。我们的研究旨在确定用于识别神经系统疾病相关VF缺陷的创新筛查网格测试的有效性。
方法：我们招募了两组参与者：我们评估了连续10例患有不同类型的神经系统疾病相关VF缺陷的成年患者的一只眼睛和每组10例对照者的一只眼睛。在每组中进行TS网格测试。灵敏度,特异性，使用24-2VFHumphrey场分析仪（HFA）作为参考标准，评估了TS网格暗点面积的阳性和阴性预测值。
结果：TS网格测试的敏感性和特异性分别为100％和90.91%，分别。曲线下面积为0.9545，95%CI为0.87-1.00。TS网格测试中的遗漏位置数与HFA24-2的视野指数之间存在显着相关性（r=0.9436，P<0.0001）。
结论：TS网格测试在检测神经系统疾病中的VF缺陷方面具有较高的敏感性和特异性。TS网格测试似乎是一个可靠的，低成本,在诊断视野缺陷的典型神经系统模式时，可以轻松替代传统的VF测试。在日常临床实践中以及在缺乏专门医疗保健服务的偏远地区，对受试者进行神经源性眼部发病率的筛查将是有用的。
方法：我们招募了两组参与者：我们评估了连续10例患有不同类型的神经系统疾病相关VF缺陷的成年患者的一只眼睛和每组10例对照者的一只眼睛。在每组中进行TS网格测试。灵敏度,特异性，使用24-2VFHumphrey场分析仪（HFA）作为参考标准，评估了TS网格暗点面积的阳性和阴性预测值。
结果：TS网格测试的敏感性和特异性分别为100％和90.91%，分别。曲线下面积为0.9545，95%CI为0.87-1.00。TS网格测试中的遗漏位置数与HFA24-2的视野指数之间存在显着相关性（r=0.9436，P<0.0001）。
结论：TS网格测试在检测神经系统疾病中的VF缺陷方面具有较高的敏感性和特异性。TS网格测试似乎是一个可靠的，低成本,在诊断视野缺陷的典型神经系统模式时，可以轻松替代传统的VF测试。在日常临床实践中以及在缺乏专门医疗保健服务的偏远地区，对受试者进行神经源性眼部发病率的筛查将是有用的。
