Abstract：
The aim of this study was to describe the in vitro activity of delafloxacin against 230 anaerobic isolates and compare it with the activity of other antimicrobials used against infections caused by anaerobic microorganisms. Minimal inhibitory concentrations (MICs) were lower for delafloxacin than for all other antibiotics tested with the exception of piperacillin-tazobactam and meropenem against Gram-positive anaerobic cocci. Only two (0.8 %) isolates of Bacteroides spp. showed a MIC ≥4 μg/mL. With some exceptions, the present results show lower MICs for delafloxacin in comparison to the other antibiotics used against anaerobes.
摘要：
这项研究的目的是描述德拉沙星对230种厌氧分离物的体外活性，并将其与其他抗微生物剂的活性进行比较。除哌拉西林-他唑巴坦和美罗培南对革兰氏阳性厌氧球菌的最低抑制浓度（MIC）低于所有其他测试的抗生素。只有两个（0.8％）拟杆菌属物种的分离株。显示MIC≥4μg/mL。除了一些例外,目前的结果表明，与其他针对厌氧菌的抗生素相比，德拉氟沙星的MIC较低。
