关键词: Ampicillin Corynebacterium striatum Infective endocarditis Native joint Native valve Septic arthritis

Mesh : Humans Female Arthritis, Infectious / microbiology diagnosis drug therapy Corynebacterium / isolation & purification Aged, 80 and over Corynebacterium Infections / microbiology diagnosis drug therapy complications Endocarditis, Bacterial / microbiology diagnosis drug therapy complications Fatal Outcome Anti-Bacterial Agents / therapeutic use Echocardiography, Transesophageal Aortic Valve / microbiology pathology diagnostic imaging

来  源:   DOI:10.1016/j.jiac.2023.12.009

Abstract:
Corynebacterium striatum occasionally causes nosocomial infections, such as catheter-related bloodstream infection and pneumonia; however, C. striatum-related infective endocarditis or septic arthritis is uncommon. We present the case of an 85-year-old woman with infective endocarditis at the native valve and septic arthritis at the native shoulder joint caused by C. striatum. The patient was admitted for a 10-day history of fever and right shoulder pain. She had no history of artificial device implantation, injury, arthrocentesis, or hospitalization. A physical examination revealed conjunctival petechiae, a systolic heart murmur, and right shoulder joint swelling. C. striatum was observed in two blood culture sets. Transesophageal echocardiography revealed vegetation in the right aortic coronary cusp. Arthrocentesis at the right shoulder aspirated pyogenic fluid and C. striatum was detected in the culture. The patient was diagnosed with infective endocarditis and septic arthritis caused by C. striatum, and ampicillin was administered based on antimicrobial susceptibility test results. The patient\'s condition was initially stable; however, she developed pulmonary congestion on day 56 and eventually died. An autopsy demonstrated perforation of the aortic left coronary cusp with vegetation. C. striatum may cause native valve endocarditis and native joint septic arthritis.
摘要:
纹状体棒状杆菌偶尔会引起医院感染,如导管相关性血流感染和肺炎;纹状体相关性感染性心内膜炎或脓毒性关节炎并不常见。我们介绍了一例85岁的女性,该女性患有由纹状体C.引起的天然瓣膜感染性心内膜炎和天然肩关节化脓性关节炎。患者因发热和右肩疼痛病史10天入院。她没有人工装置植入的病史,损伤,关节穿刺术,或住院治疗。体格检查发现结膜瘀斑,心脏收缩期杂音,右肩关节肿胀。在两组血液培养物中观察到纹状体。经食道超声心动图显示右主动脉冠状尖有植被。右肩处的关节穿刺术吸出的化脓液和培养物中检测到纹状体梭菌。患者被诊断为由纹状体梭菌引起的感染性心内膜炎和化脓性关节炎,根据抗菌药物敏感性试验结果给予氨苄西林.病人的情况最初是稳定的;然而,她在第56天出现肺充血,最终死亡。尸检显示主动脉左冠状动脉尖穿孔。纹状体梭菌可引起天然瓣膜心内膜炎和天然关节化脓性关节炎。
公众号