Abstract:
Henipaviruses are zoonotic viruses, including some highly pathogenic and capable of serious disease and high fatality rates in both animals and humans. Hendra virus and Nipah virus are the most notable henipaviruses, resulting in significant outbreaks across South Asia, South-East Asia, and Australia. Pteropid fruit bats have been identified as key zoonotic reservoirs; however, the increased discovery of henipaviruses outside the geographic distribution of Pteropid fruit bats and the detection of novel henipa-like viruses in other species such as the shrew, rat, and opossum suggest that Pteropid bats are not the sole reservoir for henipaviruses. In this review, we provide an update on henipavirus spillover events and describe the recent detection of novel unclassified henipaviruses, with a strong focus on the shrew and its emerging role as a key host of henipaviruses.
摘要:
亨尼帕病毒是人畜共患病毒,包括一些高致病性的,能够在动物和人类中严重疾病和高死亡率。亨德拉病毒和尼帕病毒是最著名的亨帕病毒,导致整个南亚的重大疫情爆发,东南亚,和澳大利亚。蕨类植物果蝙蝠已被确定为主要的人畜共患水库;然而,在蕨类动物果蝇的地理分布之外发现了更多的亨利帕病毒,并在其他物种,如泼妇中检测到了新的亨利帕类病毒,rat,负鼠和负鼠表明,翼状蝙蝠不是婴儿病毒的唯一宿主。在这次审查中,我们提供了关于流感病毒溢出事件的最新情况,并描述了最近检测到的新型未分类流感病毒,强烈关注泼妇及其作为流感病毒关键宿主的新兴角色。