PDF(Pubmed)
Abstract：
Ameloblastoma (AM), the benign counterpart of ameloblastic carcinoma, is a benign odontogenic tumor of epithelial origin, naturally aggressive, with unlimited growth potential and a high tendency to relapse if not adequately removed. Patients with AM treated surgically can benefit from dental implant therapy, promoting oral rehabilitation and improving their quality of life. The present study aimed to determine the survival rate of dental implants placed after surgical treatment of patients affected by AM. In addition, there were two secondary objectives: 1) To evaluate which dental implant loading protocols are most frequently used and 2) To determine the type of prosthetic restoration most commonly used in these patients.
The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed during the study. Searches were performed in three databases (PubMed/MEDLINE, Scopus, and Google Scholar) until November 2023. Additionally, the electronic search was enriched by an iterative hand search of journals related to oral pathology and medicine, maxillofacial surgery, and oral prosthodontics and implantology. Only reports and case series in English from January 2003 to date were included. The Joanna Briggs Institute tool (JBI-Case Reports/Case Series) was used for the study quality assessment.
The total number of patients and implants studied were 64 and 271, respectively, all with surgically treated AM. The patient\'s ages ranged from 8 to 79 years, with a mean (SD) age of 37.3 ± 16.4. Fifty-three percent were male and 47% were female. The range of follow-up duration was 1 to 22 years. An implant survival/success rate of 98.1% was reported. In addition, most of them were conventionally loaded (38.3%). Hybrid implant-supported fixed dentures were the most commonly used by prosthodontists (53%).
Oral rehabilitation with dental implants inserted in free flaps for orofacial reconstruction in surgically treated patients with AM can be considered a safe and successful treatment modality.
The Preferred Reporting Items for Systematic Review and Meta-Analysis (PRISMA) guidelines were followed during the study. Searches were performed in three databases (PubMed/MEDLINE, Scopus, and Google Scholar) until November 2023. Additionally, the electronic search was enriched by an iterative hand search of journals related to oral pathology and medicine, maxillofacial surgery, and oral prosthodontics and implantology. Only reports and case series in English from January 2003 to date were included. The Joanna Briggs Institute tool (JBI-Case Reports/Case Series) was used for the study quality assessment.
The total number of patients and implants studied were 64 and 271, respectively, all with surgically treated AM. The patient\'s ages ranged from 8 to 79 years, with a mean (SD) age of 37.3 ± 16.4. Fifty-three percent were male and 47% were female. The range of follow-up duration was 1 to 22 years. An implant survival/success rate of 98.1% was reported. In addition, most of them were conventionally loaded (38.3%). Hybrid implant-supported fixed dentures were the most commonly used by prosthodontists (53%).
Oral rehabilitation with dental implants inserted in free flaps for orofacial reconstruction in surgically treated patients with AM can be considered a safe and successful treatment modality.
摘要：
背景：成釉细胞瘤（AM），成釉细胞癌的良性对应物，是上皮起源的良性牙源性肿瘤，天生好斗，具有无限的增长潜力，如果不充分消除，则有很高的复发趋势。手术治疗AM的患者可以从种植牙治疗中受益，促进口腔康复和提高他们的生活质量。本研究旨在确定受AM影响的患者在手术治疗后放置的牙种植体的存活率。此外,有两个次要目标：1）评估最常用的牙种植体加载方案；2）确定这些患者最常用的假体修复类型。
方法：在研究期间遵循系统评价和荟萃分析（PRISMA）指南的首选报告项目。在三个数据库(PubMed/MEDLINE，Scopus,和谷歌学者)，直到2023年11月。此外,通过对口腔病理学和医学相关期刊的迭代手工搜索，丰富了电子搜索，颌面外科,口腔修复和种植学。仅包括2003年1月至今的英文报告和病例系列。JoannaBriggs研究所工具（JBI-病例报告/病例系列）用于研究质量评估。
结果：研究的患者和植入物总数分别为64和271，都用手术治疗的AM。病人的年龄从8岁到79岁不等,平均（SD）年龄为37.3±16.4。53%为男性，47%为女性。随访时间为1~22年。据报道植入物存活率/成功率为98.1%。此外,其中大多数是常规装载的(38.3%)。混合种植体支持的固定义齿是口腔修复医生最常用的（53％）。
结论：在手术治疗的AM患者中，将牙齿植入物插入游离皮瓣以进行口腔面部重建的口腔修复可以被认为是一种安全而成功的治疗方式。
方法：在研究期间遵循系统评价和荟萃分析（PRISMA）指南的首选报告项目。在三个数据库(PubMed/MEDLINE，Scopus,和谷歌学者)，直到2023年11月。此外,通过对口腔病理学和医学相关期刊的迭代手工搜索，丰富了电子搜索，颌面外科,口腔修复和种植学。仅包括2003年1月至今的英文报告和病例系列。JoannaBriggs研究所工具（JBI-病例报告/病例系列）用于研究质量评估。
结果：研究的患者和植入物总数分别为64和271，都用手术治疗的AM。病人的年龄从8岁到79岁不等,平均（SD）年龄为37.3±16.4。53%为男性，47%为女性。随访时间为1~22年。据报道植入物存活率/成功率为98.1%。此外,其中大多数是常规装载的(38.3%)。混合种植体支持的固定义齿是口腔修复医生最常用的（53％）。
结论：在手术治疗的AM患者中，将牙齿植入物插入游离皮瓣以进行口腔面部重建的口腔修复可以被认为是一种安全而成功的治疗方式。
