关键词: Bone and joint infections Infections Paediatrics (drugs and medicines) Vaccination/immunisation

Mesh : Humans Infant Anti-Bacterial Agents / therapeutic use Arthritis, Infectious / diagnosis drug therapy complications Elbow Pneumococcal Infections / diagnosis drug therapy Pneumococcal Vaccines Streptococcus pneumoniae

来  源:   DOI:10.1136/bcr-2023-256888   PDF(Pubmed)

Abstract:
Acute septic arthritis is a rare, potentially severe infection that requires immediate treatment to avoid long-term morbidity. Most common aetiological agents are commonly used for empirical treatment, but the choice of antibiotics may be influenced by other factors, such as the patient\'s age and the epidemiological context.We report an infant with elbow arthritis, whose treatment was changed after Streptococcus pneumoniae serotype 9N was isolated in the blood and synovial fluid. The child underwent arthrocentesis and received intravenous ampicillin followed by oral amoxicillin, with a favourable response and no sequelae at 1-year follow-up.We report an uncommon manifestation of invasive pneumococcal disease in a young immunised healthy infant caused by a non-vaccine serotype. The presence of S. pneumoniae should be considered in joint infections, especially in infants and those with a history of respiratory symptoms.
摘要:
急性化脓性关节炎是一种罕见的,需要立即治疗以避免长期发病的潜在严重感染。最常见的病因通常用于经验性治疗,但是抗生素的选择可能受到其他因素的影响,如患者的年龄和流行病学背景。我们报告了一个患有肘关节炎的婴儿,在血液和滑液中分离出肺炎链球菌血清型9N后,其治疗发生了变化。该患儿接受关节穿刺术,并接受静脉注射氨苄西林,然后口服阿莫西林,1年随访时反应良好,无后遗症。我们报告了由非疫苗血清型引起的年轻免疫健康婴儿的侵袭性肺炎球菌疾病的罕见表现。在关节感染中应考虑肺炎链球菌的存在,尤其是婴儿和有呼吸道症状史的人。
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