Abstract：
Only few studies on contact allergy in African countries have been published. The aim of the present study was to provide an overview of the most common contact allergens identified by the use of patch tests in African countries based on a review of the existing literature. A total of twenty-four publications from eight African countries were initially identified by search in PubMed. The abstracts and method sections were screened, and 15 studies in which patch tests were actually used to identify the allergen causing the allergic contact dermatitis (ACD) were finally selected. Nickel, cobalt, chromium, fragrance mix and p-tert-butylphenol-formaldehyde resin were the dominating contact allergens responsible for 40%-90% of the positive patch test reactions. This study indicates that a targeted effort directed towards prevention, avoidance and regulation of reliably identified contact allergens could reduce the disease burden of ACD considerable in some African countries.
摘要：
在非洲国家，关于接触过敏的研究很少发表。本研究的目的是在对现有文献进行回顾的基础上，概述通过在非洲国家使用斑贴试验确定的最常见的接触过敏原。最初在PubMed中通过搜索确定了来自八个非洲国家的总共24种出版物。对摘要和方法部分进行了筛选，最终选择了15项研究，其中实际使用斑贴试验来鉴定引起过敏性接触性皮炎（ACD）的过敏原。镍,钴,铬,香料混合物和对叔丁基苯酚甲醛树脂是主要的接触过敏原，导致40%-90%的阳性斑贴试验反应。这项研究表明，有针对性的预防工作，在一些非洲国家,避免和调节可靠确定的接触过敏原可以显著降低ACD的疾病负担.
