Abstract：
Epilepsy is a chronic brain disease with a global prevalence of 70 million people. According to the World Health Organization, roughly 5 million new cases are diagnosed every year. Anti-seizure drugs are the treatment of choice. However, in roughly one third of the patients, these drugs fail to produce the desired effect. As a result, finding novel treatments for epilepsy becomes inevitable. Recently, angiotensin receptor blockers have been proposed as a treatment to reduce the over-excitation of neurons in epilepsy. For this purpose, we conducted a review using Medline/PubMed and Google Scholar using the relevant search terms and extracted the relevant data in a table. Our review suggests that this novel approach has a very high potential to treat epilepsy, especially in those patients who fail to respond to conventional treatment options. However, more extensive and human-based trials should be conducted to reach a decisive conclusion. Nevertheless, the use of ARBs in patients with epilepsy should be carefully monitored keeping the adverse effects in mind.
摘要：
癫痫是一种慢性脑疾病，全球患病率为7000万人。根据世界卫生组织，每年大约有500万新病例被诊断出来。抗癫痫药物是治疗的选择。然而,在大约三分之一的患者中，这些药物不能产生预期的效果。因此,寻找新的治疗癫痫变得不可避免。最近,血管紧张素受体阻滞剂已被提议作为减少癫痫中神经元过度兴奋的治疗方法。为此,我们使用Medline/PubMed和GoogleScholar使用相关搜索词进行了综述,并在表格中提取了相关数据.我们的审查表明，这种新颖的方法具有非常高的潜力来治疗癫痫，尤其是那些对常规治疗方案无反应的患者。然而,应该进行更广泛和基于人类的试验，以得出决定性的结论。然而，应仔细监测癫痫患者使用ARBs的情况,同时注意不良反应.
