关键词: Arachnoid cyst Cerebellopontine angle Microsurgery Outcomes Posterior fossa Systematic review

Mesh : Humans Cerebellopontine Angle / surgery Arachnoid Cysts / surgery diagnostic imaging complications Male Female Adolescent Adult Middle Aged Aged Young Adult Child Child, Preschool Infant Neurosurgical Procedures / methods Treatment Outcome

来  源:   DOI:10.1016/j.wneu.2023.12.018

Abstract:
The role of surgical management of arachnoid cyst (AC) of the cerebellopontine angle (CPA) is uncertain. This topic has remained controversial with varying contradictory recommendations in the literature, which is limited to mostly case reports. We aimed to provide a comprehensive summary and analysis of symptoms, operative techniques, outcomes, and recurrence of all available surgical cases of AC of the CPA to date.
A systematic literature search was performed in May 2022 querying several scientific databases. Inclusion criteria specified all studies and case reports of patients with AC located at the CPA for which any relevant surgical procedures were performed.
A total of 55 patients from the literature and 5 treated at our institution were included. Mean patient age was 29 years (range, 0.08-79 years), with nearly twice (1.7×) as many female as male patients (37 female, 22 male). Headaches (35%), hearing loss (30%), vertigo (22%), and ataxia (22%) were the most common presentations. Following surgery, 95% experienced symptom improvement, with complete resolution in 64%. Of patients with hearing loss, 44% reported a return to normal. The rate of mortality was 1.69%, and 10% of tumors recurred (mean follow-up 2.3 years [range, 0-15 years].
Symptomatic AC of the CPA is rare. It exhibits a proclivity for females and commonly manifests with headache, hearing loss, vertigo, and ataxia. While careful selection for surgical candidacy is needed and intervention should be reserved for patients with severe symptoms, surgical decompression is an effective tool for symptom alleviation and recovery.
摘要:
目的:桥小脑角(CPA)蛛网膜囊肿(AC)的外科治疗的作用尚不确定。仅限于大多数病例报告,该主题一直存在争议,文献中存在各种相互矛盾的建议。在这里,我们对症状学进行了全面的总结和分析,手术技术,结果,以及所有可用手术病例的复发,到目前为止。
方法:在2022年5月进行了系统的文献检索,查询了几个科学数据库,根据PRISMA指南。纳入标准规定了在CPA进行任何相关手术类型的AC患者的所有研究和病例报告。
结果:共纳入文献中的55例患者和5例由资深作者治疗的患者。平均年龄为29岁(范围0.08-79),女性的数量几乎是男性的两倍(1.7倍);37至22。头痛(35%)听力损失(30%),眩晕(22%),共济失调(22%)是最常见的表现。手术后,95%经历了症状改善,在64%的完整分辨率。那些有听力损失的人,44%的人报告恢复正常。死亡率为1.69%,复发10%(平均随访2.3年,范围0-15)。
结论:CPA的AC症状患者是一种罕见的疾病,对女性表现出倾向性,通常表现为头痛,听力损失,眩晕,和共济失调.虽然需要仔细选择手术候选人资格,并且应该为那些有严重症状的人保留干预措施,手术减压可以作为缓解症状和恢复的有效工具。
公众号