Abstract：
OBJECTIVE: To determine the indications for fine-needle cytology and the modalities of frozen section pathological analysis in the management of salivary gland cancer.
METHODS: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group who drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group according to the formal consensus method.
RESULTS: Fine-needle cytology is recommended as part of the diagnostic work-up for a major salivary gland tumor suspicious for malignancy. Fine-needle cytology should be performed after MRI to avoid artifacts. Frozen section analysis is recommended to confirm the malignant nature of the tumor, to adapt the extent of resection and to indicate neck dissection. Whenever possible, the entire tumor and adjacent salivary or periglandular tissue should be sent for frozen section analysis.
CONCLUSIONS: Fine-needle cytology and frozen section analysis play an essential role in the management of salivary gland cancers.
METHODS: The French Network of Rare Head and Neck Tumors (REFCOR) formed a steering group who drafted a narrative review of the literature published on Medline and proposed recommendations. The level of adherence to the recommendations was then assessed by a rating group according to the formal consensus method.
RESULTS: Fine-needle cytology is recommended as part of the diagnostic work-up for a major salivary gland tumor suspicious for malignancy. Fine-needle cytology should be performed after MRI to avoid artifacts. Frozen section analysis is recommended to confirm the malignant nature of the tumor, to adapt the extent of resection and to indicate neck dissection. Whenever possible, the entire tumor and adjacent salivary or periglandular tissue should be sent for frozen section analysis.
CONCLUSIONS: Fine-needle cytology and frozen section analysis play an essential role in the management of salivary gland cancers.
摘要：
目的：确定细针细胞学检查的适应证及冰冻切片病理分析在涎腺癌治疗中的应用。
方法：法国罕见头颈部肿瘤网络（REFCOR）成立了一个指导小组，该小组对Medline上发表的文献进行了叙述性综述，并提出了建议。然后由评级小组根据正式的共识方法评估对建议的遵守程度。
结果：建议将细针细胞学检查作为可疑恶性肿瘤的主要唾液腺肿瘤的诊断工作的一部分。应在MRI后进行细针细胞学检查，以避免伪影。建议进行冰冻切片分析以确认肿瘤的恶性性质，适应切除程度并指示颈部夹层。只要有可能,应将整个肿瘤和邻近的唾液或腺周组织送去进行冰冻切片分析.
结论：细针细胞学和冰冻切片分析在唾液腺癌的治疗中起着至关重要的作用。
方法：法国罕见头颈部肿瘤网络（REFCOR）成立了一个指导小组，该小组对Medline上发表的文献进行了叙述性综述，并提出了建议。然后由评级小组根据正式的共识方法评估对建议的遵守程度。
结果：建议将细针细胞学检查作为可疑恶性肿瘤的主要唾液腺肿瘤的诊断工作的一部分。应在MRI后进行细针细胞学检查，以避免伪影。建议进行冰冻切片分析以确认肿瘤的恶性性质，适应切除程度并指示颈部夹层。只要有可能,应将整个肿瘤和邻近的唾液或腺周组织送去进行冰冻切片分析.
结论：细针细胞学和冰冻切片分析在唾液腺癌的治疗中起着至关重要的作用。
