国际浆液性液体细胞病理学报告系统(TIS)的开发是为了使报告浆液样品分析的卫生专业人员之间的交流标准化。类别包括非诊断(ND)、恶性肿瘤(NFM)阴性,不确定的重要性(AUS),可疑恶性肿瘤(SFM)恶性(MAL)。每个类别的特征在于恶性肿瘤(ROM)的风险。我们进行了文献综述,以使用几种来源分析与TIS相关的研究,包括PubMed,随后搜索相关的细胞病理学杂志网站(美国癌症协会,诊断性细胞病理学,美国细胞病理学学会杂志,和细胞学和细胞病理学)。该搜索包括2020年1月至2023年12月发表的文章,使用术语“国际和浆液系统”。“我们确定了257篇文章,其中20项涉及纳入和排除标准。每个类别的总体ROM为ND的23.55%,NFM占16.46%,澳大利亚50.78%,SFM为91.34%,和98.21%的MAL。考虑到TIS推荐的ROM速率,ND类别在建议的间隔之间,而SFM类别比率高于预期。其他类别(NFM,AUS,和MAL)低于预期值。SFM和MAL与恶性结果有更强的相关性。需要新的研究来准确地从TIS中确定每个类别的ROM率。
BACKGROUND: The International Serous Fluid
Cytopathology Reporting System (TIS) was developed to standardize communication among health professionals reporting analyses of serous fluid samples. The categories include non-diagnosis (ND), negative for malignancy (NFM), atypia of undetermined significance (AUS), suspected malignancy (SFM), and malignant (MAL). Each category was characterized by a risk of malignancy (ROM).
METHODS: We performed a literature review to analyze studies related to TIS using several sources, including PubMed, followed by a search of relevant
cytopathology journal websites (American Cancer Society, Diagnostic
Cytopathology, Journal of the American Society of
Cytopathology, and Acta Cytologica and
Cytopathology). The search included articles published between January 2020 and December 2023, using the terms \"international AND serous fluid system.\"
RESULTS: We identified 257 articles, of which 20 addressed the inclusion and exclusion criteria. The overall ROMs for each category were 23.55% for ND, 16.46% for NFM, 50.78% for AUS, 91.34% for SFM, and 98.21% for MAL.
CONCLUSIONS: Considering the TIS-recommended ROM rates, the ND category was between the suggested intervals, while the SFM category rate was bigger than expected. The other categories (NFM, AUS, and MAL) were below expected values. SFM and MAL had a stronger association with MAL results. New studies are needed to determine each category\'s ROM rate from TIS accurately.