UNASSIGNED: Seventeen infants of trisomy 18 admitted to our center between 2007 and 2019 were retrospectively studied. We divided the patients into a non-intensive group (n = 5) and an intensive group (n = 12) and evaluated their perinatal background and survival-related outcomes of the two groups.
UNASSIGNED: The 1- and 3-year survival rates were both 33% in the intensive group, which was significantly higher than that in the non-intensive group (p < 0.001). Half of the infants in the intensive care group were discharged alive, whereas in the non-intensive care group, all died during hospitalization (p = 0.049).
UNASSIGNED: Neonatal intensive care for neonates with 18 trisomy significantly improved not only survival rates but also survival-discharge rates. Our findings would be helpful in providing 18 trisomy neonates with standard neonatal intensive care when discussing medical care with their parents.
■对2007年至2019年期间入住我们中心的17名18三体婴儿进行了回顾性研究。我们将患者分为非强化组(n=5)和强化组(n=12),并评估了两组的围产期背景和生存相关结局。
■强化组的1年和3年生存率均为33%,显著高于非密集组(p<0.001)。重症监护组中有一半的婴儿存活出院,而在非重症监护组中,所有患者均在住院期间死亡(p=0.049).
■对18三体新生儿的新生儿重症监护不仅显着提高了生存率,而且还提高了生存率。在与父母讨论医疗护理时,我们的发现将有助于为18名三体性新生儿提供标准的新生儿重症监护。