Abstract：
This report describes a case of Stage III Grade C periodontitis requiring periodontal regenerative therapy. The patient was a 19-year-old woman who presented with the chief complaint of gingival recession in the incisor region. An initial examination revealed that 45.3% of sites had a probing depth of ≥4 mm and 45.8% bleeding on probing. Radiographic examination showed angular bone resorption in #25, 26, 31, 36, and 46 and horizontal resorption in other regions. Initial periodontal therapy was implemented based on a clinical diagnosis of Stage III Grade C periodontitis (generalized aggressive periodontitis). Occlusal adjustment was also performed at sites showing premature contact (#26 and 36) after suppression of inflammation. Periodontal regenerative therapy using recombinant human fibroblast growth factor (rhFGF) -2 was performed on #25, 26, and 46. Combination therapy with rhFGF-2 and deproteinized bovine bone mineral (DBBM) was performed on #31 and 36. A non-incised papillae surgical approach (NIPSA) was used on #31. Periodontal conditions were then re-evaluated and the patient placed on supportive periodontal therapy. Regenerative therapy using rhFGF-2 and DBBM with NIPSA yielded an improvement in clinical parameters and bone resorption. This improvement has been adequately maintained over a 12-month period. Continued care is needed to maintain stable periodontal conditions.
摘要：
本报告描述了需要牙周再生治疗的III级C级牙周炎病例。该患者是一名19岁的妇女，主要主诉门牙区域牙龈萎缩。初步检查显示，有45.3％的部位的探查深度≥4mm，探查时出血为45.8％。射线照相检查显示＃25、26、31、36和46中的角骨吸收和其他区域的水平吸收。基于III期C级牙周炎(广泛性侵袭性牙周炎)的临床诊断实施初始牙周治疗。在抑制炎症后,还在显示过早接触的部位(#26和#36)进行咬合调整。使用重组人成纤维细胞生长因子(rhFGF)-2的牙周再生治疗在#25、26和46上进行。在#31和36上进行rhFGF-2和去蛋白牛骨矿物质(DBBM)的联合治疗。在#31上使用非切开乳头手术方法(NIPSA)。然后重新评估牙周状况，并对患者进行支持牙周治疗。使用rhFGF-2和DBBM与NIPSA的再生疗法在临床参数和骨吸收方面产生了改善。这种改善在12个月内得到了充分的维持。需要持续护理以保持稳定的牙周状况。
