Abstract:
One previously undescribed prenylated flavonoid (1) and three known ones (2-4) were isolated from leaves of Epimedium brevicornu maxim. Their structures were determined through extensive spectroscopic analysis and comparison with the NMR data in the literature. Compound 1 showed a moderate cytotoxicity with an IC50 value of 18.7 μM, while known compounds 2 and 3 elicited weak cytotoxicities with IC50 values of 29.2 and 32.8 μM against Lewis Lung cancer cells (LLC cells), respectively.
摘要:
从淫羊藿的叶子中分离出一种先前未描述的异戊烯化类黄酮(1)和三种已知类黄酮(2-4)。通过广泛的光谱分析并与文献中的NMR数据进行比较,确定了它们的结构。化合物1显示中等细胞毒性,IC50值为18.7μM,而已知的化合物2和3对Lewis肺癌细胞(LLC细胞)的IC50值分别为29.2和32.8μM,分别。