%0 Journal Article
%T One new prenylated flavonoid with cytotoxic activity from Epimedium brevicornu maxim.
%A Zhang H
%A Wang Y
%A Liang Y
%A Zhao X
%A Chen G
%J Nat Prod Res
%V 0
%N 0
%D 2023 Nov 15
%M 37966979
%F 2.488
%R 10.1080/14786419.2023.2282114
%X One previously undescribed prenylated flavonoid (1) and three known ones (2-4) were isolated from leaves of Epimedium brevicornu maxim. Their structures were determined through extensive spectroscopic analysis and comparison with the NMR data in the literature. Compound 1 showed a moderate cytotoxicity with an IC50 value of 18.7 μM, while known compounds 2 and 3 elicited weak cytotoxicities with IC50 values of 29.2 and 32.8 μM against Lewis Lung cancer cells (LLC cells), respectively.