Mesh : Pregnancy Female Humans Young Adult Adult Eclampsia / drug therapy Posterior Leukoencephalopathy Syndrome / chemically induced complications diagnosis Magnesium Seizures / chemically induced complications Brain Edema / chemically induced diagnostic imaging

来  源:   DOI:10.1213/XAA.0000000000001726

Abstract:
Posterior reversible encephalopathy syndrome (PRES) is a rare neurologic condition and a feared complication of eclampsia. It is evidenced by acute neurologic dysfunction secondary to cerebral edema and is typically reversible in nature. Although it is a relatively new diagnosis, an increasing amount of literature has described its occurrence, including an association with hypomagnesemia. We present a case wherein a 24-year-old parturient developed PRES and eclampsia in the setting of symptomatic hypermagnesemia, requiring management with lorazepam after seizures developed. Here we detail her clinical course, including the unique challenges of treating eclampsia and PRES in the setting of magnesium toxicity.
摘要:
后部可逆性脑病综合征(PRES)是一种罕见的神经系统疾病,是子痫的可怕并发症。它由继发于脑水肿的急性神经功能障碍证明,并且本质上通常是可逆的。虽然这是一个相对较新的诊断,越来越多的文献描述了它的发生,包括与低镁血症有关。我们提出了一个病例,其中一名24岁的产妇在有症状的高镁血症的情况下发展为PRES和子痫,癫痫发作后需要使用劳拉西泮治疗。在这里,我们详细介绍了她的临床课程,包括在镁毒性的背景下治疗子痫和PRES的独特挑战。
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