Abstract：
Short-chain chlorinated paraffins (SCCPs) are listed in the Stockholm Convention. Therefore, selecting suitable methods for their accurate quantification is essential. Nowadays, the quality of commercial reagents employed as quantification standards is not guaranteed. As a solution, we adopted an SCCP formulation reference material with known homolog composition ratios as the quantification standard to evaluate the appropriateness of the methods. By mixing the SCCP formulation and interferences, an analytical sample was independently prepared and used as the simulation environmental sample. The homolog compositional profiles of the SCCPs resembled those of the quantification standard and the analytical sample. The mass fractions and the homolog profiles, including the carbon chain length and chlorine homolog profiles, of the SCCPs were reported by 14 different laboratories. For the mass fraction, the results reported by participants were consistent, except for the participants that employed low-resolution gas chromatography (GC). The results generated from liquid chromatography (LC) and GC were slightly different, despite of the similar homolog composition ratios between the quantification standard and the analytical sample. Although there were discreet discrepancies in the overall chlorine homolog profiles, the carbon chain length profiles acquired from GC and LC were similar. The differences depended on the method employed. Additionally, compared with the low-resolution data, the high-resolution data displayed less fluctuation since the effect of the interferences on the analytical sample was reduced because of the mass accuracy of high-resolution instruments. Accordingly, the interlaboratory trial employing the similar homolog compositional profiles of the quantification standard and the analytical sample proved valuable in elucidating the differences among methods, considering equipment, resolution specification, and ionization.
摘要：
短链氯化石蜡（短链氯化石蜡）被列入《斯德哥尔摩公约》。因此,选择合适的方法对它们的准确量化至关重要。如今,不能保证用作定量标准的商业试剂的质量。作为解决方案,我们采用具有已知同源物组成比的SCCP制剂参考材料作为定量标准,以评估方法的适当性.通过混合SCCP配方和干扰，独立制备分析样品并用作模拟环境样品。短链氯化石蜡的同系物组成概况类似于定量标准和分析样品。质量分数和同系物轮廓，包括碳链长度和氯同系物，14个不同的实验室报告了短链氯化石蜡。对于质量分数，参与者报告的结果是一致的，除了使用低分辨率气相色谱法（GC）的参与者。液相色谱（LC）和GC产生的结果略有不同，尽管定量标准和分析样品之间的同源组成比相似。尽管在整个氯同系物中存在差异，从GC和LC获得的碳链长度分布相似。差异取决于所采用的方法。此外,与低分辨率数据相比，由于高分辨率仪器的质量精度降低了干扰对分析样品的影响，因此高分辨率数据的波动较小。因此，实验室间试验采用相似的同系物组成的定量标准和分析样品证明有价值的方法之间的差异，考虑到设备，分辨率规格，和电离。
