关键词: cognition cognitive diseases dietary interventions millet nutrition

Mesh : Millets / genetics Nootropic Agents Quality of Life Cognition Antioxidants

来  源:   DOI:10.1002/mnfr.202300450

Abstract:
Cognition is the mental processes and abilities involved in acquiring, storing, retrieving and using it for decision making. Cognitive decline due to aging, lifestyle factor, chronic health conditions, genetic, and environmental factors are rising global concern and propose a potential threat to the cognitive health. The nutritional imbalance has led to increase in cognitive disorders around the world. Millets can be a nutritional intervention for promoting cognitive health and preventing cognitive decline. Millets has abundant phenolic compounds, flavonoids, and antioxidants to protect against oxidative stress-induced cognitive impairment. Millets exert neuroprotective effects by modulating pathways involved in neuronal-survival, synaptic-plasticity, and release of brain-derived neurotrophic factor. Millets demonstrates anti-inflammatory properties by regulating inflammatory-pathways and suppressing cytokines associated with cognitive impairment. Millets maintain healthy gut microbiota by producing metabolites such as short-chain fatty acids, which influence brain function and cognition. However, further research is needed to elucidate the underlying mechanisms and on optimizing the proportion do exploit its potential. Implementing millet-based dietary strategies through public health initiatives and educational programs can be a practical approach to support cognitive health across populations. Harnessing the potential of millets as a nutritional intervention offers a promising avenue for promoting cognitive health and improving the quality of life.
摘要:
认知是指获得所涉及的心理过程和能力,存储,检索并用于决策。由于衰老导致的认知能力下降,生活方式因素,慢性健康状况,遗传,和环境因素正在引起全球关注,并提出了对认知健康的潜在威胁。营养失衡导致世界各地认知障碍的增加。小米可以作为促进认知健康和预防认知衰退的营养干预手段。谷子含有丰富的酚类化合物,黄酮类化合物,和抗氧化剂,以防止氧化应激诱导的认知障碍。小米通过调节参与神经元存活的途径发挥神经保护作用,突触可塑性,和脑源性神经营养因子的释放。小米通过调节炎症途径和抑制与认知障碍相关的细胞因子而表现出抗炎特性。小米通过产生代谢产物如短链脂肪酸来维持健康的肠道菌群,影响大脑功能和认知。然而,需要进一步的研究来阐明潜在的机制,并在优化比例方面发挥其潜力。通过公共卫生计划和教育计划实施基于小米的饮食策略可以成为支持人群认知健康的实用方法。利用小米作为营养干预的潜力为促进认知健康和改善生活质量提供了一条有希望的途径。
公众号