Abstract：
BACKGROUND: Dermatologic surgeons are increasingly using surgical adhesives in their practice. Studies comparing sutured wounds to those that utilize a combination of suturing and skin adhesive have not been previously conducted.
OBJECTIVE: To compare the cosmetic outcome and patient wound care satisfaction of an intermediate suture closure with an intermediate suture closure followed by the application of 2-octyl cyanoacrylate (2-OCA).
METHODS: Fifty patients were enrolled in a randomized, evaluator-blinded, split-scar study. Following intermediate sutured closure of a surgical defect, one side of the wound was randomized to receive an additional application of 2-OCA. After 3 months, the scar was assessed using the POSAS tool and patients reported wound care preferences.
RESULTS: As the primary outcome measure, the mean sum of observer POSAS was 12.80 for sutured closure alone versus 12.40 for sutured closures followed by 2-OCA (P = .49).
CONCLUSIONS: Single-center study of a relatively homogenous population.
CONCLUSIONS: Although there were no significant differences in scar cosmesis, both patients and observers tended to prefer the side with an additional application of 2-OCA in most POSAS components, in overall opinion, and in patient wound care satisfaction. Dermatologic surgeons may add this to their practice without sacrificing scar outcomes or patient satisfaction.
OBJECTIVE: To compare the cosmetic outcome and patient wound care satisfaction of an intermediate suture closure with an intermediate suture closure followed by the application of 2-octyl cyanoacrylate (2-OCA).
METHODS: Fifty patients were enrolled in a randomized, evaluator-blinded, split-scar study. Following intermediate sutured closure of a surgical defect, one side of the wound was randomized to receive an additional application of 2-OCA. After 3 months, the scar was assessed using the POSAS tool and patients reported wound care preferences.
RESULTS: As the primary outcome measure, the mean sum of observer POSAS was 12.80 for sutured closure alone versus 12.40 for sutured closures followed by 2-OCA (P = .49).
CONCLUSIONS: Single-center study of a relatively homogenous population.
CONCLUSIONS: Although there were no significant differences in scar cosmesis, both patients and observers tended to prefer the side with an additional application of 2-OCA in most POSAS components, in overall opinion, and in patient wound care satisfaction. Dermatologic surgeons may add this to their practice without sacrificing scar outcomes or patient satisfaction.
摘要：
背景：皮肤科医生在实践中越来越多地使用外科粘合剂。以前没有进行过将缝合的伤口与使用缝合和皮肤粘合剂的组合的伤口进行比较的研究。
目的：比较中间缝合闭合与中间缝合闭合后应用2-氰基丙烯酸辛酯的美容效果和患者伤口护理满意度。
方法：50名患者被纳入随机，评估者致盲，裂痕研究.在手术缺损的中间缝合闭合后，伤口一侧随机接受额外应用氰基丙烯酸2-辛酯.三个月后,使用POSAS工具评估疤痕，患者报告伤口护理偏好。
结果：作为主要结果指标，单独缝合闭合的观察者POSAS的平均总和为12.80,其次是2-OCA(p=0.49).
结论：相对同质人群的单中心研究。
结论：虽然瘢痕外观没有显著差异，患者和观察者都倾向于在大多数POSAS组件中包含额外应用2-OCA的一面，总的来说，以及患者伤口护理满意度。皮肤科医生可以在不牺牲疤痕结果或患者满意度的情况下将其添加到他们的实践中。
目的：比较中间缝合闭合与中间缝合闭合后应用2-氰基丙烯酸辛酯的美容效果和患者伤口护理满意度。
方法：50名患者被纳入随机，评估者致盲，裂痕研究.在手术缺损的中间缝合闭合后，伤口一侧随机接受额外应用氰基丙烯酸2-辛酯.三个月后,使用POSAS工具评估疤痕，患者报告伤口护理偏好。
结果：作为主要结果指标，单独缝合闭合的观察者POSAS的平均总和为12.80,其次是2-OCA(p=0.49).
结论：相对同质人群的单中心研究。
结论：虽然瘢痕外观没有显著差异，患者和观察者都倾向于在大多数POSAS组件中包含额外应用2-OCA的一面，总的来说，以及患者伤口护理满意度。皮肤科医生可以在不牺牲疤痕结果或患者满意度的情况下将其添加到他们的实践中。
