{Reference Type}: Randomized Controlled Trial
{Title}: Aesthetic outcome of intermediate closure versus intermediate closure followed by 2-octyl cyanoacrylate: A randomized evaluator-blinded split-wound comparative effectiveness trial.
{Author}: Kwapnoski Z;Doost MS;Vy M;Eisen DB;
{Journal}: J Am Acad Dermatol
{Volume}: 90
{Issue}: 3
{Year}: 2024 Mar 20
{Factor}: 15.487
{DOI}: 10.1016/j.jaad.2023.10.028
{Abstract}: <B>BACKGROUND: </B>Dermatologic surgeons are increasingly using surgical adhesives in their practice. Studies comparing sutured wounds to those that utilize a combination of suturing and skin adhesive have not been previously conducted.<BR><B>OBJECTIVE: </B>To compare the cosmetic outcome and patient wound care satisfaction of an intermediate suture closure with an intermediate suture closure followed by the application of 2-octyl cyanoacrylate (2-OCA).<BR><B>METHODS: </B>Fifty patients were enrolled in a randomized, evaluator-blinded, split-scar study. Following intermediate sutured closure of a surgical defect, one side of the wound was randomized to receive an additional application of 2-OCA. After 3 months, the scar was assessed using the POSAS tool and patients reported wound care preferences.<BR><B>RESULTS: </B>As the primary outcome measure, the mean sum of observer POSAS was 12.80 for sutured closure alone versus 12.40 for sutured closures followed by 2-OCA (P = .49).<BR><B>CONCLUSIONS: </B>Single-center study of a relatively homogenous population.<BR><B>CONCLUSIONS: </B>Although there were no significant differences in scar cosmesis, both patients and observers tended to prefer the side with an additional application of 2-OCA in most POSAS components, in overall opinion, and in patient wound care satisfaction. Dermatologic surgeons may add this to their practice without sacrificing scar outcomes or patient satisfaction.