METHODS: Clinical research questions relevant to the objective of the document were identified, and reformulated into PICO format (patient, intervention, comparison, outcome) by a panel of experts selected based on their experience in the field. A systematic review of the available evidence was conducted, and evidence was graded according to GRADE (Grading of Recommendations Assessment, Development, and Evaluation) criteria. Subsequently, recommendations were developed.
RESULTS: Three PICO questions were constructed referring to uveitis anterior, non-anterior and complicated with macular edema. A total of 19 recommendations were formulated, based on the evidence found and/or expert consensus.
CONCLUSIONS: Here we present the first official recommendations of the Spanish Society of Rheumatology for the treatment of non-infectious and non-demyelinating disease associated uveitis. They can be directly applied to the Spanish healthcare system as a tool for assistance and therapeutic homogenisation.
方法:确定了与文件目的相关的临床研究问题,并重新配制成PICO格式(患者,干预,比较,结果)由一个专家小组根据他们在该领域的经验选出。对现有证据进行了系统审查,证据根据等级(建议评估等级,发展,和评估)标准。随后,提出了建议。
结果:构建了三个PICO问题,涉及前葡萄膜炎,非前并并发黄斑水肿。共提出19项建议,根据发现的证据和/或专家共识。
结论:这里我们提出了西班牙风湿病学会关于治疗非感染性和非脱髓鞘疾病相关葡萄膜炎的第一个官方建议。它们可以直接应用于西班牙医疗保健系统,作为援助和治疗均质化的工具。