PDF(Pubmed)
Abstract：
Histoplasma capsulatum is a dimorphic fungus found in certain parts of North, Central, and South America. Transmission is primarily through airborne inoculation from inhaled fungal microconidia. Histoplasmosis is typically a self-limited mycosis; however, in patients with immunodeficiency, disseminated disease can occur and may lead to high disease burden. This report studies a case of disseminated histoplasmosis in a patient newly diagnosed with human immunodeficiency virus. His presentation on admission was consistent with infectious pulmonary granulomatous disease, and further imaging and laboratory results showed evidence of multi-organ involvement. It is likely his presentation in Central California was a reactivation infection after inoculation in Central America many years ago.
摘要：
荚膜组织支原体是在北方某些地区发现的双态真菌，中央,和南美洲。传播主要是通过吸入的真菌微分生孢子的空气传播接种。组织胞浆菌病通常是自限性真菌病；然而，在免疫缺陷患者中，播散性疾病可能发生，并可能导致高疾病负担。本报告研究了一例新诊断为人类免疫缺陷病毒的患者的播散性组织胞浆菌病。他入院时的表现与感染性肺肉芽肿病一致，进一步的影像学和实验室结果显示多器官受累的证据。他在加利福尼亚中部的演讲很可能是多年前在中美洲接种疫苗后的重新激活感染。
