%0 Case Reports
%T Disseminated Histoplasmosis in Central California Seen in an Immunocompromised Patient.
%A Ghadiya K
%A Dunn R
%A Singh G
%A Lai H
%A Garcia-Pacheco R
%J J Investig Med High Impact Case Rep
%V 11
%N 0
%D 2023 Jan-Dec
%M 37811883
暂无%R 10.1177/23247096231205347
%X Histoplasma capsulatum is a dimorphic fungus found in certain parts of North, Central, and South America. Transmission is primarily through airborne inoculation from inhaled fungal microconidia. Histoplasmosis is typically a self-limited mycosis; however, in patients with immunodeficiency, disseminated disease can occur and may lead to high disease burden. This report studies a case of disseminated histoplasmosis in a patient newly diagnosed with human immunodeficiency virus. His presentation on admission was consistent with infectious pulmonary granulomatous disease, and further imaging and laboratory results showed evidence of multi-organ involvement. It is likely his presentation in Central California was a reactivation infection after inoculation in Central America many years ago.