{Reference Type}: Case Reports
{Title}: Disseminated Histoplasmosis in Central California Seen in an Immunocompromised Patient.
{Author}: Ghadiya K;Dunn R;Singh G;Lai H;Garcia-Pacheco R;
{Journal}: J Investig Med High Impact Case Rep
{Volume}: 11
{Issue}: 0
{Year}: 2023 Jan-Dec
暂无{DOI}: 10.1177/23247096231205347
{Abstract}: Histoplasma capsulatum is a dimorphic fungus found in certain parts of North, Central, and South America. Transmission is primarily through airborne inoculation from inhaled fungal microconidia. Histoplasmosis is typically a self-limited mycosis; however, in patients with immunodeficiency, disseminated disease can occur and may lead to high disease burden. This report studies a case of disseminated histoplasmosis in a patient newly diagnosed with human immunodeficiency virus. His presentation on admission was consistent with infectious pulmonary granulomatous disease, and further imaging and laboratory results showed evidence of multi-organ involvement. It is likely his presentation in Central California was a reactivation infection after inoculation in Central America many years ago.