Abstract：
OBJECTIVE: The aim of this study is to determine the accuracy of transvaginal ultrasound (TVU) for the diagnosis of ureteral involvement in women with deep infiltrating endometriosis (DIE).
METHODS: The meta-analysis included primary studies comparing the use of TVU for diagnosing endometriotic involvement of the ureter, using laparoscopic surgery and histological diagnosis as the reference standard. Search was performed in several databases (Scopus, Web of Science, and PubMed/MEDLINE). The studies\' quality and bias risk were assessed using the Quality Assessment of Diagnostic Accuracy Study-2 (QUADAS-2). Diagnostic performance was estimated by assessing pooled sensitivity and specificity.
RESULTS: A total of 496 citations were found. Six articles were ultimately selected for this systematic review and meta-analysis after the inclusion and exclusion criteria were applied. Pooled sensitivity and specificity were 0.81 (95% CI: 0.42-0.96), 1.00 (95% CI: 0.93-1.00). The heterogeneity observed was high for both sensitivity and specificity. Overall risk of bias was low.
CONCLUSIONS: TVU is a valuable tool for the pre-operative identification of ureteral involvement by DIE.
METHODS: The meta-analysis included primary studies comparing the use of TVU for diagnosing endometriotic involvement of the ureter, using laparoscopic surgery and histological diagnosis as the reference standard. Search was performed in several databases (Scopus, Web of Science, and PubMed/MEDLINE). The studies\' quality and bias risk were assessed using the Quality Assessment of Diagnostic Accuracy Study-2 (QUADAS-2). Diagnostic performance was estimated by assessing pooled sensitivity and specificity.
RESULTS: A total of 496 citations were found. Six articles were ultimately selected for this systematic review and meta-analysis after the inclusion and exclusion criteria were applied. Pooled sensitivity and specificity were 0.81 (95% CI: 0.42-0.96), 1.00 (95% CI: 0.93-1.00). The heterogeneity observed was high for both sensitivity and specificity. Overall risk of bias was low.
CONCLUSIONS: TVU is a valuable tool for the pre-operative identification of ureteral involvement by DIE.
摘要：
目的：本研究的目的是确定经阴道超声（TVU）诊断深部浸润型子宫内膜异位症（DIE）女性输尿管受累的准确性。
方法：荟萃分析包括比较使用TVU诊断子宫内膜异位累及输尿管的主要研究。以腹腔镜手术和组织学诊断为参考标准。在多个数据库中进行了搜索(Scopus，WebofScience,和PubMed/MEDLINE）。使用诊断准确性质量评估研究2（QUADAS-2）评估研究质量和偏倚风险。通过评估合并的敏感性和特异性来评估诊断性能。
结果：共发现496篇引文。在应用纳入和排除标准后，最终选择六篇文章进行系统评价和荟萃分析。合并的敏感性和特异性为0.81(95%CI：0.42-0.96)，1.00（95%CI：0.93-1.00）。观察到的异质性在敏感性和特异性方面都很高。总体偏倚风险较低。
结论：TVU是DIE术前识别输尿管受累的有价值的工具。
方法：荟萃分析包括比较使用TVU诊断子宫内膜异位累及输尿管的主要研究。以腹腔镜手术和组织学诊断为参考标准。在多个数据库中进行了搜索(Scopus，WebofScience,和PubMed/MEDLINE）。使用诊断准确性质量评估研究2（QUADAS-2）评估研究质量和偏倚风险。通过评估合并的敏感性和特异性来评估诊断性能。
结果：共发现496篇引文。在应用纳入和排除标准后，最终选择六篇文章进行系统评价和荟萃分析。合并的敏感性和特异性为0.81(95%CI：0.42-0.96)，1.00（95%CI：0.93-1.00）。观察到的异质性在敏感性和特异性方面都很高。总体偏倚风险较低。
结论：TVU是DIE术前识别输尿管受累的有价值的工具。
