Abstract：
In type 1 diabetes (T1D), pancreatic beta cells are destroyed by the immune system, causing chronic hyperglycemia and micro and macrovascular complications. However, some people experience a \'honeymoon\' phase (or partial remission) after being diagnosed with type 1 diabetes. During this phase, a substantial amount of insulin is still produced by the pancreas, helping to reduce blood sugar levels and the requirement for external insulin. The clinical significance of this phase lies in the potential for pharmacological and non-pharmacological interventions during this time frame to either slow down or arrest beta-cell destruction. Clearly, we need to continue researching novel therapies like immunomodulatory agents, but we also need to look at potentially effective therapies with acceptable side effects that can serve as a complement to the medicines currently being studied. Physical activity and exercise, regardless of its type, is one of the factors its impact on the control of diabetes is being investigated and promising results have been achieved. Although there are still limited reports in this regard, there is some evidence to suggest that regular physical exercise could prolong the honeymoon period in both adults and children. In this review, having described the immune base of type 1 diabetes, we outline the benefits of exercise on the general health of individuals with T1D. Moreover, we centered on the honeymoon and current evidence suggesting the effects of physical activity and exercise on this phase duration.
摘要：
在1型糖尿病（T1D）中，胰腺β细胞被免疫系统破坏,引起慢性高血糖和微血管和大血管并发症。然而,有些人在被诊断为1型糖尿病后经历“蜜月期”（或部分缓解期）。在这个阶段,胰腺仍然产生大量的胰岛素，有助于降低血糖水平和对外部胰岛素的需求。这一阶段的临床意义在于在这段时间内药理和非药理干预的潜力，以减缓或阻止β细胞的破坏。显然,我们需要继续研究免疫调节剂等新疗法，但我们还需要研究潜在有效的治疗方法，这些治疗具有可接受的副作用，可以作为目前正在研究的药物的补充。身体活动和锻炼，不管它的类型，是其对糖尿病控制的影响因素之一，目前正在研究中，并取得了有希望的结果。尽管这方面的报道仍然有限,有证据表明，有规律的体育锻炼可以延长成人和儿童的蜜月期。在这次审查中,描述了1型糖尿病的免疫基础，我们概述了运动对T1D患者总体健康的益处.此外，我们集中在蜜月和目前的证据表明，身体活动和锻炼对这一阶段的影响。
