Abstract：
OBJECTIVE: This review aims to assess structural, chemical, and mechanical properties of coronal dentin after endodontic irrigation.
METHODS: Reporting followed the PRISMA extension for scoping reviews. An electronic search was carried out in PubMed, Embase, and Cochrane Library. Records filtered by language and published up to November 4, 2022 were independently screened by two researchers. Studies evaluating structural, chemical, or mechanical properties of human permanent coronal dentin after irrigation within the scope of nonsurgical root canal treatment were included. Data were extracted regarding study type, sample description and size, experimental groups, outcome, evaluation method, and main findings.
RESULTS: From the initial 1916 studies, and by adding 2 cross-references, 11 in vitro studies were included. Seven studies provide ultrastructural and/or chemical characterization, and six assessed microhardness and/or flexural strength. One percent to 8% sodium hypochlorite (NaOCl) and 1%-17% ethylenediaminetetraacetic acid (EDTA) were the most commonly tested solutions, with contact times of 2-240 min (NaOCl) and 1-1440 min (EDTA) being evaluated.
CONCLUSIONS: Overall, the literature is consensual regarding the inevitable impact of NaOCl and chelating agents on coronal dentin, with both deproteinizing and decalcifying effects being concentration- and time-dependent. The alteration of mechanical parameters further confirmed the surface and subsurface ultrastructural and chemical changes.
CONCLUSIONS: Endodontic treatment success highly depends on restorative sealing. Understanding the result of exposing coronal dentin, the main substrate for bonding, to irrigants\' action is crucial. The deproteinizing and decalcifying effects of NaOCl and chelating agents are both concentration- and time-dependent, causing surface and subsurface ultrastructural, chemical, and mechanical alterations.
METHODS: Reporting followed the PRISMA extension for scoping reviews. An electronic search was carried out in PubMed, Embase, and Cochrane Library. Records filtered by language and published up to November 4, 2022 were independently screened by two researchers. Studies evaluating structural, chemical, or mechanical properties of human permanent coronal dentin after irrigation within the scope of nonsurgical root canal treatment were included. Data were extracted regarding study type, sample description and size, experimental groups, outcome, evaluation method, and main findings.
RESULTS: From the initial 1916 studies, and by adding 2 cross-references, 11 in vitro studies were included. Seven studies provide ultrastructural and/or chemical characterization, and six assessed microhardness and/or flexural strength. One percent to 8% sodium hypochlorite (NaOCl) and 1%-17% ethylenediaminetetraacetic acid (EDTA) were the most commonly tested solutions, with contact times of 2-240 min (NaOCl) and 1-1440 min (EDTA) being evaluated.
CONCLUSIONS: Overall, the literature is consensual regarding the inevitable impact of NaOCl and chelating agents on coronal dentin, with both deproteinizing and decalcifying effects being concentration- and time-dependent. The alteration of mechanical parameters further confirmed the surface and subsurface ultrastructural and chemical changes.
CONCLUSIONS: Endodontic treatment success highly depends on restorative sealing. Understanding the result of exposing coronal dentin, the main substrate for bonding, to irrigants\' action is crucial. The deproteinizing and decalcifying effects of NaOCl and chelating agents are both concentration- and time-dependent, causing surface and subsurface ultrastructural, chemical, and mechanical alterations.
摘要：
目的：这篇综述旨在评估结构，化学,牙髓冲洗后冠状牙本质的力学性质。
方法：报告遵循PRISMA扩展范围审查。在PubMed进行了电子搜索，Embase,科克伦图书馆通过语言过滤并发布到2022年11月4日的记录由两名研究人员独立筛选。评估结构的研究，化学,包括非手术根管治疗范围内冲洗后的人永久性冠状牙本质的机械性能。提取有关研究类型的数据，样品描述和尺寸，实验组,结果,评价方法，和主要发现。
结果：从最初的1916年研究来看，通过添加2个交叉引用，包括11项体外研究。七项研究提供了超微结构和/或化学表征，和六个评估的显微硬度和/或弯曲强度。1％至8％的次氯酸钠（NaOCl）和1％-17％的乙二胺四乙酸（EDTA）是最常用的测试溶液，评估接触时间为2-240分钟（NaOCl）和1-1440分钟（EDTA）。
结论：总体而言，关于NaOCl和螯合剂对冠状牙本质的不可避免的影响，脱蛋白和脱钙作用都是浓度和时间依赖性的。力学参数的改变进一步证实了表面和亚表面的超微结构和化学变化。
结论：牙髓治疗的成功在很大程度上取决于修复性密封。了解暴露冠状牙本质的结果，用于粘合的主要基材，灌溉者的行动是至关重要的。NaOCl和螯合剂的脱蛋白和脱钙作用具有浓度和时间依赖性,导致表面和地下超微结构，化学,和机械改造。
方法：报告遵循PRISMA扩展范围审查。在PubMed进行了电子搜索，Embase,科克伦图书馆通过语言过滤并发布到2022年11月4日的记录由两名研究人员独立筛选。评估结构的研究，化学,包括非手术根管治疗范围内冲洗后的人永久性冠状牙本质的机械性能。提取有关研究类型的数据，样品描述和尺寸，实验组,结果,评价方法，和主要发现。
结果：从最初的1916年研究来看，通过添加2个交叉引用，包括11项体外研究。七项研究提供了超微结构和/或化学表征，和六个评估的显微硬度和/或弯曲强度。1％至8％的次氯酸钠（NaOCl）和1％-17％的乙二胺四乙酸（EDTA）是最常用的测试溶液，评估接触时间为2-240分钟（NaOCl）和1-1440分钟（EDTA）。
结论：总体而言，关于NaOCl和螯合剂对冠状牙本质的不可避免的影响，脱蛋白和脱钙作用都是浓度和时间依赖性的。力学参数的改变进一步证实了表面和亚表面的超微结构和化学变化。
结论：牙髓治疗的成功在很大程度上取决于修复性密封。了解暴露冠状牙本质的结果，用于粘合的主要基材，灌溉者的行动是至关重要的。NaOCl和螯合剂的脱蛋白和脱钙作用具有浓度和时间依赖性,导致表面和地下超微结构，化学,和机械改造。
