关键词: Quercus Toxicology case report cow intoxication kidney tubular necrosis oak pasture

来  源:   DOI:10.3390/ani13162678   PDF(Pubmed)

Abstract:
Oak poisoning is a known intoxication in grazing animals, but is slightly described in the literature. This case report describes 7 cattle from 3 different farms admitted to the clinic for ruminants of the University of Liège for suspected acorn poisoning in the autumn of 2022. The clinical signs were, anorexia, apathy with polyuria with low density. Further investigations led to the diagnosis of renal failure (blood urea 162 ± 88 mg/dL; blood creatinine 12 ± 4 mg/L). Supportive treatment, based on infusions (NaCl 0.9%) and electrolyte rebalancing, was administered and renal values were assessed every 24-48 h. Of these animals, 5/7 were euthanized. At necropsy, digestive erosions and ulcerations, oedema and renal hemorrhages, between the pyloric/caliceal cavity and the medulla were observed. Histopathological examination revealed necrosis of the renal tubules. The renal values of the two remaining animals were reduced, their general condition improved, and they were discharged. Acorn poisoning is a serious disease with no specific antidote or characteristic symptoms. Animals are identified as sick too late, when renal failure is already established. Farmers should be made more aware in order to prevent exposure, especially in years when acorns are abundant. Furthermore, there is no antidote for this intoxication.
摘要:
橡树中毒是一种已知的放牧动物中毒,但在文献中略有描述。该病例报告描述了2022年秋季,来自3个不同农场的7头牛因怀疑橡子中毒而被送往列日大学反刍动物诊所。临床症状是,厌食症,有低密度多尿的冷漠。进一步的调查导致肾衰竭的诊断(血尿素162±88mg/dL;血肌酐12±4mg/L)。支持性治疗,基于输液(NaCl0.9%)和电解质再平衡,每24-48小时评估一次肾脏值。在这些动物中,5/7被安乐死。尸检时,消化道糜烂和溃疡,水肿和肾出血,在幽门/钙腔和延髓之间观察到。组织病理学检查显示肾小管坏死。其余两只动物的肾脏值降低,他们的总体状况有所改善,他们已经出院了.橡子中毒是一种严重的疾病,没有特定的解毒剂或特征性症状。动物被认为生病太晚了,当肾功能衰竭已经成立。应该让农民更加意识到,以防止接触,尤其是在橡子丰富的年代。此外,这种中毒没有解药。
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