关键词: giant parathyroid adenoma (GPTA) hypercalcemia hypocalcemia nephrolithiasis primary hyperparathyroidism renal stones

来  源:   DOI:10.1097/MS9.0000000000001005   PDF(Pubmed)

Abstract:
Nephrolithiasis, a common urological disease, could indicate a more ominous pathology beyond the kidneys. Patients who present with renal stones must be investigated for serum calcium and subsequently parathyroid hormones, if indicated, as one of the clinical presentations of primary hyperparathyroidism is renal stones.
UNASSIGNED: A 48-year-old married female with a past medical history significant for renal stones presented to the clinic chiefly complaining of muscle pain, joint pain, and fatigue. After thorough investigations, she was diagnosed with a case of primary hyperparathyroidism due to parathyroid adenoma and was managed surgically according to guidelines.
UNASSIGNED: Hypercalcemia, serum calcium of greater than 2 standard deviations above the reference value, is commonly seen to be associated with parathyroid mass therefore, assessment of serum calcium is a necessary step toward the diagnosis of parathyroid adenoma in cases with recurrent renal stones.
UNASSIGNED: Recurrent nephrolithiasis requires more thorough investigation for the possible underlying cause. Primary hyperparathyroidism due to parathyroid adenoma can present with recurrent renal stones and some vague symptoms.
摘要:
肾结石,一种常见的泌尿系统疾病,可能表明肾脏以外更不祥的病理。患有肾结石的患者必须进行血清钙和随后的甲状旁腺激素的调查,如果指示,原发性甲状旁腺功能亢进的临床表现之一是肾结石。
一位48岁的已婚女性,有肾结石病史,主要是肌肉疼痛,关节痛,和疲劳。经过彻底调查,她被诊断为1例因甲状旁腺腺瘤引起的原发性甲状旁腺功能亢进,并按照指南进行了手术治疗.
高钙血症,血清钙高于参考值2个标准偏差,因此,通常被认为与甲状旁腺肿块有关,在复发性肾结石患者中,血清钙的评估是诊断甲状旁腺腺瘤的必要步骤。
复发性肾结石需要对可能的根本原因进行更彻底的调查。甲状旁腺腺瘤引起的原发性甲状旁腺功能亢进可表现为复发性肾结石和一些模糊的症状。
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