Abstract:
The chemical analysis on the aerial sections of Eupatorium adenophorum Spreng. resulted in the identification of four unprecedented 5/5 fused bicyclosesquiterpenoids, eupatorid A (1), and its analogues named eupatorester A-C (2-4) using various chromatographic techniques. Their structures were unambiguously confirmed by detailed spectroscopic investigations (including 1D, 2D-NMR and HRMS), and single crystal X-ray diffraction. The anti-inflammatory activities, in vitro tumor growth inhibitory activities and antibacterial activities of these compounds were evaluated.
摘要:
紫茎泽兰地上部分的化学分析。结果鉴定出四种前所未有的5/5融合双环半萜,EupatoridA(1),及其类似物使用各种色谱技术命名为eupatoresterA-C(2-4)。通过详细的光谱研究(包括1D,2D-NMR和HRMS),和单晶X射线衍射。抗炎活性,评价了这些化合物的体外肿瘤生长抑制活性和抗菌活性。