PDF(Pubmed)
Abstract：
Mitral annular plane systolic excursion (MAPSE) is a simple and reliable index for evaluating left ventricular (LV) systolic function, particularly in patients with poor image quality; however, the lack of reference values limits its widespread use. This study aimed to establish the normal ranges for MAPSE measured using motion-mode (M-mode) and two-dimensional speckle tracking echocardiography (2D-STE) and to explore its principal determinants.
This multicentre, prospective, cross-sectional study included 1952 healthy participants [840 men (43%); age range, 18-80 years] from 55 centres. MAPSE was measured using M-mode echocardiography and 2D-STE. The results showed that women had a higher MAPSE than men and MAPSE decreased with age. The age- and sex-specific reference values for MAPSE were established for these two methods. Multiple linear regression analyses revealed that MAPSE on M-mode echocardiography correlated with age and MAPSE on 2D-STE with age, blood pressure (BP), heart rate, and LV volume. Moreover, MAPSE measured by 2D-STE correlated more strongly with global longitudinal strain compared with that measured using M-mode echocardiography.
Normal MAPSE reference values were established based on age and sex. BP, heart rate, and LV volume are potential factors that influence MAPSE and should be considered in clinical practice. Normal values are useful for evaluating LV longitudinal systolic function, especially in patients with poor image quality, and may further facilitate the use of MAPSE in routine assessments.
This multicentre, prospective, cross-sectional study included 1952 healthy participants [840 men (43%); age range, 18-80 years] from 55 centres. MAPSE was measured using M-mode echocardiography and 2D-STE. The results showed that women had a higher MAPSE than men and MAPSE decreased with age. The age- and sex-specific reference values for MAPSE were established for these two methods. Multiple linear regression analyses revealed that MAPSE on M-mode echocardiography correlated with age and MAPSE on 2D-STE with age, blood pressure (BP), heart rate, and LV volume. Moreover, MAPSE measured by 2D-STE correlated more strongly with global longitudinal strain compared with that measured using M-mode echocardiography.
Normal MAPSE reference values were established based on age and sex. BP, heart rate, and LV volume are potential factors that influence MAPSE and should be considered in clinical practice. Normal values are useful for evaluating LV longitudinal systolic function, especially in patients with poor image quality, and may further facilitate the use of MAPSE in routine assessments.
摘要：
目的：二尖瓣环平面收缩偏移（MAPSE）是评估左心室（LV）收缩功能的简单可靠指标，特别是在图像质量差的患者中；然而，参考值的缺乏限制了其广泛使用。本研究旨在建立使用运动模式（M模式）和二维斑点追踪超声心动图（2D-STE）测量的MAPSE的正常范围，并探讨其主要决定因素。
结果：这个多中心，prospective,横断面研究包括1,952名健康参与者(840名男性[43%]；年龄范围，18-80岁）来自55个中心。使用M型超声心动图和2D-STE测量MAPSE。结果表明，女性的MAPSE高于男性，且MAPSE随年龄增长而下降。为这两种方法建立了MAPSE的年龄和性别特异性参考值。多元线性回归分析显示，M型超声心动图MAPSE与年龄相关，2D-STEMAPSE与年龄相关，血压,心率,和LV音量。此外，与使用M型超声心动图测量的MAPSE相比，通过2D-STE测量的MAPSE与全局纵向应变的相关性更强。
结论：正常MAPSE参考值是根据年龄和性别确定的。血压,心率,和LV体积是影响MAPSE的潜在因素，应在临床实践中加以考虑。正常值可用于评价左心室纵向收缩功能,尤其是图像质量差的患者，并可能进一步促进MAPSE在常规评估中的使用。
结果：这个多中心，prospective,横断面研究包括1,952名健康参与者(840名男性[43%]；年龄范围，18-80岁）来自55个中心。使用M型超声心动图和2D-STE测量MAPSE。结果表明，女性的MAPSE高于男性，且MAPSE随年龄增长而下降。为这两种方法建立了MAPSE的年龄和性别特异性参考值。多元线性回归分析显示，M型超声心动图MAPSE与年龄相关，2D-STEMAPSE与年龄相关，血压,心率,和LV音量。此外，与使用M型超声心动图测量的MAPSE相比，通过2D-STE测量的MAPSE与全局纵向应变的相关性更强。
结论：正常MAPSE参考值是根据年龄和性别确定的。血压,心率,和LV体积是影响MAPSE的潜在因素，应在临床实践中加以考虑。正常值可用于评价左心室纵向收缩功能,尤其是图像质量差的患者，并可能进一步促进MAPSE在常规评估中的使用。
