关键词: Autopsy Forensic pathology Forensic toxicology Paraquat poisoning Pesticide poisoning

来  源:   DOI:10.1177/19253621231184612   PDF(Pubmed)

Abstract:
Paraquat is a highly toxic agent used as an herbicide worldwide. Despite its easy and widespread availability, data regarding cases of paraquat poisoning in India is limited. Diagnosis often becomes difficult without a clear history, owing to its rather nonspecific and varying presentation. In the present case, a 22-year-old man was brought with a history of high-grade fever, sore throat, and oral ulcers for around a week. He was symptomatically treated at multiple hospitals and was worked up for suspected diagnoses like diphtheria and influenza (H1N1). Later during treatment, it was revealed that \"Paraxzone\" was procured online by the patient himself two weeks before the onset of his symptoms. Thence, the treatment regimen was modified following suspicion of paraquat poisoning. However, the delay in diagnosis led to the worsening his condition, and the patient succumbed to death due to pulmonary and renal complications after 16 days of survival. The postmortem examination, supplemented with histopathological evaluation, supported the diagnosis of paraquat poisoning. Paraquat poisoning can mimic a myriad of clinical conditions. Thorough history taking, a high degree of suspicion, and collaborative work with the investigating agency are of paramount importance while dealing with cases of suspected paraquat poisoning in hospital settings.
摘要:
百草枯是世界范围内用作除草剂的剧毒剂。尽管它容易和广泛的可用性,有关印度百草枯中毒事件的数据有限。没有明确的病史,诊断往往变得困难,由于其相当非特异性和不同的表现。在目前的情况下,一名22岁的男子被带来有高烧史,喉咙痛,口腔溃疡持续一周左右.他在多家医院接受了对症治疗,并因白喉和流感(H1N1)等可疑诊断而接受了治疗。在治疗过程中,据透露,“Paraxzone”是在症状发作前两周由患者本人在线购买的。从那里,在怀疑百草枯中毒后,对治疗方案进行了修改.然而,诊断的延误导致他的病情恶化,患者存活16天后因肺部和肾脏并发症而死亡。验尸,补充组织病理学评估,支持百草枯中毒的诊断.百草枯中毒可以模拟无数的临床情况。彻底的历史,高度怀疑,在医院处理怀疑百草枯中毒事件时,与调查机构的合作至关重要。
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