Abstract：
BACKGROUND: Tooth bleaching imparts whitening effects along with adverse effects such as increased tooth sensitivity and enamel surface changes. Herein, we employed optical coherence tomography (OCT), a nondestructive optical detection technique, for evaluation of tooth enamel after treatment with peroxide-based bleaching agents.
METHODS: Fifteen enamel samples were bleached using 38% acidic hydrogen peroxide-based bleach, subjected to OCT scanning, and then cross-sectioned and imaged under polarized light microscopy (PLM) and transverse microradiography (TMR). OCT cross-sectional images were compared with PLM and TMR. The depth and severity of demineralization produced in the bleached enamel were measured by OCT, PLM, and TMR. Comparison between the three techniques was performed using Kruskal-Wallis H non-parametric test and Pearson correlation.
RESULTS: In comparison with PLM and TMR, OCT clearly detected the changes in the enamel surface after hydrogen peroxide bleaching. Significant correlations (p<0.05) were observed in lesion depth between OCT and PLM (r=0.820), OCT and TMR (r=0.822), and TMR and PLM (r=0.861). There was no statistically significant difference in demineralization depth values measured by OCT, PLM, and TMR (p>0.05).
CONCLUSIONS: OCT can allow real-time, non-invasive imaging of artificially bleached tooth models and automatically measure the early changes in the enamel lesion structure upon exposure to hydrogen peroxide-based bleaching agents.
METHODS: Fifteen enamel samples were bleached using 38% acidic hydrogen peroxide-based bleach, subjected to OCT scanning, and then cross-sectioned and imaged under polarized light microscopy (PLM) and transverse microradiography (TMR). OCT cross-sectional images were compared with PLM and TMR. The depth and severity of demineralization produced in the bleached enamel were measured by OCT, PLM, and TMR. Comparison between the three techniques was performed using Kruskal-Wallis H non-parametric test and Pearson correlation.
RESULTS: In comparison with PLM and TMR, OCT clearly detected the changes in the enamel surface after hydrogen peroxide bleaching. Significant correlations (p<0.05) were observed in lesion depth between OCT and PLM (r=0.820), OCT and TMR (r=0.822), and TMR and PLM (r=0.861). There was no statistically significant difference in demineralization depth values measured by OCT, PLM, and TMR (p>0.05).
CONCLUSIONS: OCT can allow real-time, non-invasive imaging of artificially bleached tooth models and automatically measure the early changes in the enamel lesion structure upon exposure to hydrogen peroxide-based bleaching agents.
摘要：
背景：牙齿漂白会产生美白效果，并产生不利影响，例如牙齿敏感性增加和牙釉质表面变化。在这里，我们采用了光学相干断层扫描（OCT），一种无损的光学检测技术，用于评估用过氧化物基漂白剂处理后的牙釉质。
方法：使用38%酸性过氧化氢基漂白剂漂白15个搪瓷样品，进行OCT扫描,然后在偏振光显微镜（PLM）和横向显微照相（TMR）下进行横截面和成像。将OCT横截面图像与PLM和TMR进行比较。通过OCT测量漂白釉质中产生的脱矿质的深度和严重程度，PLM,还有TMR.使用Kruskal-WallisH非参数检验和Pearson相关性对三种技术进行比较。
结果：与PLM和TMR相比，OCT清楚地检测到过氧化氢漂白后釉质表面的变化。在OCT和PLM(r=0.820)的病变深度中观察到显著相关性(p<0.05),OCT和TMR（r=0.822），TMR和PLM(r=0.861)。OCT测量的脱矿质深度值无统计学差异,PLM,和TMR(p>0.05)。
结论：OCT可以允许实时，对人工漂白的牙齿模型进行非侵入性成像，并自动测量暴露于基于过氧化氢的漂白剂后牙釉质病变结构的早期变化。
方法：使用38%酸性过氧化氢基漂白剂漂白15个搪瓷样品，进行OCT扫描,然后在偏振光显微镜（PLM）和横向显微照相（TMR）下进行横截面和成像。将OCT横截面图像与PLM和TMR进行比较。通过OCT测量漂白釉质中产生的脱矿质的深度和严重程度，PLM,还有TMR.使用Kruskal-WallisH非参数检验和Pearson相关性对三种技术进行比较。
结果：与PLM和TMR相比，OCT清楚地检测到过氧化氢漂白后釉质表面的变化。在OCT和PLM(r=0.820)的病变深度中观察到显著相关性(p<0.05),OCT和TMR（r=0.822），TMR和PLM(r=0.861)。OCT测量的脱矿质深度值无统计学差异,PLM,和TMR(p>0.05)。
结论：OCT可以允许实时，对人工漂白的牙齿模型进行非侵入性成像，并自动测量暴露于基于过氧化氢的漂白剂后牙釉质病变结构的早期变化。
