PDF(Pubmed)
Abstract：
A 33-year-old woman developed hypertensive emergency (268/168 mmHg) with renal failure and hypertensive retinopathy. Four hours after the initiation of antihypertensive therapy with the continuous infusion of nicardipine, her blood pressure (BP) decreased to 168/84 mmHg; however, the patient developed blindness. She was diagnosed with posterior ischemic optic neuropathy (PION). Her BP was maintained at approximately 175/90 mmHg until her vision improved. Olmesartan was initiated on day 13, and her BP decreased to approximately 135/95 mmHg without the re-exacerbation of vision loss. Although the prognosis of PION is poor, its early diagnosis and gradual antihypertensive therapy may help preserve the patient\'s vision.
摘要：
一名33岁妇女出现高血压急症（268/168mmHg），伴有肾衰竭和高血压视网膜病变。开始持续输注尼卡地平的抗高血压治疗后四小时，她的血压（BP）降至168/84mmHg;然而，病人出现了失明。她被诊断为后部缺血性视神经病变（PION）。她的血压维持在约175/90mmHg直到她的视力改善。在第13天开始服用奥美沙坦，她的血压降至约135/95mmHg，但视力丧失没有再加重。虽然PION的预后较差,其早期诊断和逐步降压治疗可能有助于保护患者的视力。
