{Reference Type}: Case Reports
{Title}: A Successfully Treated Case of Posterior Ischemic Optic Neuropathy That Developed during Antihypertensive Therapy for Hypertensive Emergency.
{Author}: Yonezawa Y;Koga K;Higashi Y;Hasebe M;Fukushima C;Omiya C;Nishioka K;Yahata K;
{Journal}: Intern Med
{Volume}: 63
{Issue}: 4
{Year}: 2024 Feb 15
{Factor}: 1.282
{DOI}: 10.2169/internalmedicine.1550-23
{Abstract}: A 33-year-old woman developed hypertensive emergency (268/168 mmHg) with renal failure and hypertensive retinopathy. Four hours after the initiation of antihypertensive therapy with the continuous infusion of nicardipine, her blood pressure (BP) decreased to 168/84 mmHg; however, the patient developed blindness. She was diagnosed with posterior ischemic optic neuropathy (PION). Her BP was maintained at approximately 175/90 mmHg until her vision improved. Olmesartan was initiated on day 13, and her BP decreased to approximately 135/95 mmHg without the re-exacerbation of vision loss. Although the prognosis of PION is poor, its early diagnosis and gradual antihypertensive therapy may help preserve the patient's vision.