Abstract：
Anti-hypertensive medications may affect plasma renin activity and/or plasma aldosterone concentration, misleading the interpretation of the aldosterone-to-renin ratio when screening for primary aldosteronism. The Task Force of Taiwan PA recommends that, when necessary, using α-adrenergic receptor blocking agents, centrally acting α-adrenergic agonists, and/or non-dihydropyridine calcium channel blockers should be considered to control blood pressure before screening for PA. We recommend temporarily holding β-adrenergic receptor blocking agents, mineralocorticoid receptor antagonists, dihydropyridine calcium channel blockers, angiotensin-converting enzyme inhibitors, angiotensin II receptor blockers, and all diuretics before screening for PA. Further large-scale randomized controlled studies are required to confirm the recommendations.
摘要：
抗高血压药物可能会影响血浆肾素活性和/或血浆醛固酮浓度，在筛查原发性醛固酮增多症时，对醛固酮与肾素比值的解释产生误导。台湾巴勒斯坦权力机构特别工作组建议，必要时,使用α-肾上腺素受体阻断剂，中枢作用α-肾上腺素能激动剂，在筛查PA之前，应考虑使用和/或非二氢吡啶类钙通道阻滞剂来控制血压。我们建议暂时服用β-肾上腺素受体阻断剂,盐皮质激素受体拮抗剂，二氢吡啶类钙通道阻滞剂，血管紧张素转换酶抑制剂，血管紧张素II受体阻滞剂，和所有利尿剂前筛查PA。需要进一步的大规模随机对照研究来确认建议。
