Abstract：
The leaves of Vernonia amygdalina Delile of the family Asteraceae(also known as "bitter leaf"), rich in biological activities, are used as both medicine and food for a long time in West tropical Africa. They have been introduced into Southeast Asia and Fujian and Guangdong provinces of China in recent years. However, little is known about the properties of the plant in traditional Chinese medicine(TCM), which limits its combination with other Chinese medicinal herbs. In this study, 473 articles on V. amygdalina leaves were selected from PubMed, Web of Science, CNKI, Wanfang Data and VIP to summarize their components, pharmacological effects and clinical research. V. amygdalina leaves presented anti-microbial, hypoglycemic, anti-hypertensive, lipid-lowering, anti-tumor, anti-inflammatory, antioxidant, and other pharmacological effects. On the basis of the theory of TCM properties, the leaves were inferred to be cold in property and bitter and sweet in flavor, acting on spleen, liver, stomach and large intestine and with the functions of clearing heat, drying dampness, purging fire, removing toxin, killing insects and preventing attack of malaria. They can be used to treat dampness-heat diarrhea, interior heat and diabetes, malaria, insect accumulation and eczema(5-10 g dry leaves by decoction per day and an appropriate amount of crushed fresh leaves applying to the affected area for external use). Due to the lack of TCM properties, V. amygdalina leaves are rarely used medicinally in China. The determination of medicinal properties of the leaves is conducive to the introduction of new exotic medicinal herbs and the development of new TCM resources, which facilitated further clinical application and research and development of Chinese medicinal herbs.
摘要：
菊科VernoniaamygdalinaDelile的叶子（也称为苦叶），丰富的生物活动，在热带西非长期被用作药物和食品。近年来，它们已被引入东南亚以及中国的福建和广东省。然而,对植物在中药(TCM)中的特性知之甚少，这限制了它与其他中草药的结合。在这项研究中,从PubMed中选择了473篇关于杏仁核叶片的文章，WebofScience,CNKI,万方数据和VIP总结了它们的组成部分，药理作用和临床研究。V.杏仁叶呈现抗微生物，低血糖,抗高血压，降脂，抗肿瘤，抗炎,抗氧化剂，和其他药理作用。在中药属性理论的基础上,这些叶子被推断为性质冷，味道苦而甜，作用于脾脏,肝脏,胃和大肠，具有清热的功能，干湿，吹扫火,去除毒素,杀死昆虫，防止疟疾发作。它们可以用来治疗湿热腹泻，内热和糖尿病，疟疾,昆虫积累和湿疹（每天煎5-10g干叶，并将适量的压碎的新鲜叶子应用于受影响的区域供外部使用）。由于缺乏中药的属性，V.杏仁叶在中国很少药用。叶的药用性质的测定有利于引进新的外来药材和开发新的中药资源,促进了中药的进一步临床应用和研发。
