Abstract：
In this study, sugarcane molasses essential oils (SMEOs) were extracted by microwave-assisted hydrodistillation (MAHD); the components of SMEOs were identified and analyzed by gas chromatography-mass spectrometry (GC-MS). SMEOs were loaded into mesoporous silica nanoparticles (MSNPs) and their sustained-release activity was evaluated. In vivo anti-inflammatory activity assays pertained to inhibiting the auricle swelling caused by xylene in mice, the peritoneal permeability increased inflammation in mice induced by acetic acid and the inflammation caused by granuloma hyperplasia in mice. We demonstrated that the main components of SMEOs were isoamylol, ethyl acetate, isobutanol, isovaleraldehyde, 2-methyl-butanal, furfural and 2-acetylpyrrole. The SMEOs loaded into MSNPs formed MSNP-SMEOs, which enhanced the stability and slow-release performance compared with SMEOs. The main components of SMEOs can inhibit inflammation, and the development and application of SMEOs in the fields of food and medicine have certain potential.
摘要：
在这项研究中,通过微波辅助加氢蒸馏（MAHD）提取甘蔗糖蜜精油（SMEOs）；通过气相色谱-质谱（GC-MS）鉴定和分析SMEOs的成分。将SMEO加载到介孔二氧化硅纳米颗粒（MSNP）中，并评估其持续释放活性。体内抗炎活性测定与抑制小鼠二甲苯引起的耳廓肿胀有关，腹腔通透性增加乙酸诱导的小鼠炎症和肉芽肿增生引起的小鼠炎症。我们证明了SMEOs的主要成分是异淀粉醇，乙酸乙酯,异丁醇,异戊醛，2-甲基-丁醛,糠醛和2-乙酰吡咯。加载到MSNP中的SMEO形成了MSNP-SMEO，与SMEO相比，提高了稳定性和缓释性能。SMEOs的主要成分可以抑制炎症，SMEOs在食品和医药领域的开发和应用具有一定的潜力。
