PDF(Pubmed)
Abstract：
BACKGROUND: Eosinophilic fasciitis (EF) is a rare connective tissue disease that can cause swelling and sclerosis of the extremities, and special attention is needed to differentiate EF from systemic sclerosis. Misdiagnosis or omission markedly delays treatment of EF, and severe skin sclerosis in advanced stages can cause joint contracture and tendon retraction, worsening the patient\'s prognosis and quality of life.
METHODS: We report a case of EF in a young woman diagnosed by tissue biopsy, confirming the difficulty of differential diagnosis with scleroderma.
CONCLUSIONS: Focusing on skin manifestations, completing tissue biopsy and radiography can help diagnose EF effectively. Clinicians should enhance their understanding of the differences between EF and scleroderma, and early diagnosis and standardized treatment can improve the prognosis of patients with EF.
METHODS: We report a case of EF in a young woman diagnosed by tissue biopsy, confirming the difficulty of differential diagnosis with scleroderma.
CONCLUSIONS: Focusing on skin manifestations, completing tissue biopsy and radiography can help diagnose EF effectively. Clinicians should enhance their understanding of the differences between EF and scleroderma, and early diagnosis and standardized treatment can improve the prognosis of patients with EF.
摘要：
背景：嗜酸性筋膜炎（EF）是一种罕见的结缔组织疾病，可引起四肢肿胀和硬化，需要特别注意区分EF和系统性硬化症。误诊或漏诊明显延误EF的治疗，晚期严重的皮肤硬化会导致关节挛缩和肌腱缩回，恶化患者的预后和生活质量。
方法：我们报告一例年轻女性经组织活检确诊为EF，确认与硬皮病鉴别诊断的困难。
结论：关注皮肤表现，完成组织活检和X线摄影术可以帮助有效诊断EF。临床医生应加强对EF与硬皮病差异的认识,早期诊断和规范化治疗可改善EF患者的预后。
方法：我们报告一例年轻女性经组织活检确诊为EF，确认与硬皮病鉴别诊断的困难。
结论：关注皮肤表现，完成组织活检和X线摄影术可以帮助有效诊断EF。临床医生应加强对EF与硬皮病差异的认识,早期诊断和规范化治疗可改善EF患者的预后。
