PDF(Pubmed)
Abstract：
The true incidence of acute gastrointestinal illness in China is underrecognized by surveillance systems. The aims of this study were to estimate the incidence and prevalence of self-reported AGI in the community of China, and to investigate sociodemographic and epidemiological determinants of AGI.
We conducted a 12-months cross-sectional population-based survey in eight provinces of China during 2014-2015. The survey determined the prevalence and incidence of acute gastrointestinal illness (AGI) in the total permanent resident population in China according to the census of the population in 2010. The random multilevel population sample was stratified by geographic, population, and socioeconomic status. We used a recommended case definition of AGI, with diarrhea (three loose or watery stools) and/or any vomiting in a four-week recall. A face-to-face survey was conducted by selecting the member in the household with the most recent birthday.
Among 56,704 sampled individuals, 948 (1,134 person-time) fulfilled the case definition; 98.5% reported diarrhea. This corresponds to 2.3% (95% CI:1.9%-2.8%) of an overall standardized four-week prevalence and 0.3 (95% CI: 0.23-0.34) episodes per person-year of annual adjusted incidence rate. There was no significant difference between males and females. The incidence rates were higher among urban residents, and in the spring and summer. In the whole study period, 50% of the cases sought medical care, of which 3.9% were hospitalized and 14.3% provided a biological sample for laboratory identification of the causative agent. Children aged 0-4 and young adults aged 15-24, people living in rural areas and people who traveled frequently had higher prevalence of AGI.
Results showed that AGI represents a substantial burden in China, and will contribute to the estimation of the global burden of AGI. Complemented with data on the etiologies of AGI, these estimates will form the basis to estimate the burden of foodborne diseases in China.
We conducted a 12-months cross-sectional population-based survey in eight provinces of China during 2014-2015. The survey determined the prevalence and incidence of acute gastrointestinal illness (AGI) in the total permanent resident population in China according to the census of the population in 2010. The random multilevel population sample was stratified by geographic, population, and socioeconomic status. We used a recommended case definition of AGI, with diarrhea (three loose or watery stools) and/or any vomiting in a four-week recall. A face-to-face survey was conducted by selecting the member in the household with the most recent birthday.
Among 56,704 sampled individuals, 948 (1,134 person-time) fulfilled the case definition; 98.5% reported diarrhea. This corresponds to 2.3% (95% CI:1.9%-2.8%) of an overall standardized four-week prevalence and 0.3 (95% CI: 0.23-0.34) episodes per person-year of annual adjusted incidence rate. There was no significant difference between males and females. The incidence rates were higher among urban residents, and in the spring and summer. In the whole study period, 50% of the cases sought medical care, of which 3.9% were hospitalized and 14.3% provided a biological sample for laboratory identification of the causative agent. Children aged 0-4 and young adults aged 15-24, people living in rural areas and people who traveled frequently had higher prevalence of AGI.
Results showed that AGI represents a substantial burden in China, and will contribute to the estimation of the global burden of AGI. Complemented with data on the etiologies of AGI, these estimates will form the basis to estimate the burden of foodborne diseases in China.
摘要：
背景：中国急性胃肠道疾病的真实发病率未被监测系统认识到。这项研究的目的是估计中国社区自我报告的AGI的发病率和患病率，并调查AGI的社会人口统计学和流行病学决定因素。
方法：我们在2014-2015年期间在中国八个省份进行了为期12个月的基于人群的横断面调查。该调查根据2010年的人口普查，确定了中国常住人口中急性胃肠道疾病（AGI）的患病率和发病率。随机多水平人口样本按地理分层，人口,和社会经济地位。我们使用了AGI的推荐案例定义，在四周的召回中出现腹泻（三张松散或水样大便）和/或任何呕吐。通过选择最近生日的家庭成员进行了面对面的调查。
结果：在56,704个样本中，948（1,134人次）符合病例定义；98.5%报告腹泻。这相当于2.3%(95%CI:1.9%-2.8%)的总体标准化四周患病率和0.3(95%CI:0.23-0.34)的年调整发病率。男性和女性之间没有显着差异。城市居民发病率较高，在春天和夏天。在整个学习期间,50%的病例寻求医疗护理,其中3.9%住院，14.3%提供生物样本用于实验室鉴定病原体。0-4岁的儿童和15-24岁的年轻人，生活在农村地区的人和经常旅行的人患有AGI。
结论：结果表明，AGI在中国是一个巨大的负担，并将有助于估计AGI的全球负担。补充了AGI病因的数据，这些估计将成为估计中国食源性疾病负担的基础。
方法：我们在2014-2015年期间在中国八个省份进行了为期12个月的基于人群的横断面调查。该调查根据2010年的人口普查，确定了中国常住人口中急性胃肠道疾病（AGI）的患病率和发病率。随机多水平人口样本按地理分层，人口,和社会经济地位。我们使用了AGI的推荐案例定义，在四周的召回中出现腹泻（三张松散或水样大便）和/或任何呕吐。通过选择最近生日的家庭成员进行了面对面的调查。
结果：在56,704个样本中，948（1,134人次）符合病例定义；98.5%报告腹泻。这相当于2.3%(95%CI:1.9%-2.8%)的总体标准化四周患病率和0.3(95%CI:0.23-0.34)的年调整发病率。男性和女性之间没有显着差异。城市居民发病率较高，在春天和夏天。在整个学习期间,50%的病例寻求医疗护理,其中3.9%住院，14.3%提供生物样本用于实验室鉴定病原体。0-4岁的儿童和15-24岁的年轻人，生活在农村地区的人和经常旅行的人患有AGI。
结论：结果表明，AGI在中国是一个巨大的负担，并将有助于估计AGI的全球负担。补充了AGI病因的数据，这些估计将成为估计中国食源性疾病负担的基础。
