PDF(Pubmed)
Abstract：
Plants have evolved two layers of protection against biotic stress: PAMP-triggered immunity (PTI) and effector-triggered immunity (ETI). The primary mechanism of ETI involves nucleotide-binding leucine-rich repeat immune receptors (NLRs). Although NLR genes have been studied in several plant species, a comprehensive database of NLRs across a diverse array of species is still lacking. Here, we present a thorough analysis of NLR genes across 100 high-quality plant genomes (PlantNLRatlas). The PlantNLRatlas includes a total of 68,452 NLRs, of which 3,689 are full-length and 64,763 are partial-length NLRs. The majority of NLR groups were phyletically clustered. In addition, the domain sequences were found to be highly conserved within each NLR group. Our PlantNLRatlas dataset is complementary to RefPlantNLR, a collection of NLR genes which have been experimentally confirmed. The PlantNLRatlas should prove helpful for comparative investigations of NLRs across a range of plant groups, including understudied taxa. Finally, the PlantNLRatlas resource is intended to help the field move past a monolithic understanding of NLR structure and function.
摘要：
植物已经进化出两层针对生物胁迫的保护:PAMP触发的免疫(PTI)和效应子触发的免疫(ETI)。ETI的主要机制涉及核苷酸结合的富含亮氨酸的重复免疫受体（NLR）。尽管已经在几种植物物种中研究了NLR基因，仍然缺乏跨各种物种的NLR的综合数据库。这里,我们对100个高质量植物基因组（PlantNLRatlas）中的NLR基因进行了全面分析。PlantNLRatlas总共包括68,452NLR，其中3,689是全长的，64,763是部分长度的NLR。大多数NLR组是系统成簇的。此外,发现结构域序列在每个NLR组中高度保守.我们的PlantNLRatlas数据集是RefPlantNLR的补充，已被实验证实的NLR基因的集合。ThePlantNLRatlasshouldprovehelpfulforcomparativeinvestigationofNLRacrossarangeofplantgroups,包括未研究的分类群。最后,PlantNLRatlas资源旨在帮助该领域超越对NLR结构和功能的整体理解。
