关键词: intra-arterial chemotherapy intra-vitreal chemotherapy retinoblastoma

Mesh : Humans Infant Retinoblastoma / drug therapy Retinal Neoplasms / drug therapy Conservative Treatment Consensus South America Retrospective Studies

来  源:   DOI:10.1002/pbc.30352

Abstract:
Local therapies are increasingly used for ocular preservation in retinoblastoma. In middle-income countries, these techniques pose specific challenges mostly related to more advanced disease at diagnosis. The Grupo de America Latina de Oncología Pediátrica (GALOP) developed a consensus document for the management of conservative therapy for retinoblastoma. Intra-arterial chemotherapy (OAC) is the preferred therapy, except for those with less advanced disease or age younger than 6 months. OAC allowed for a reduction in the use of external beam radiotherapy in our setting. Intravitreal chemotherapy is the preferred treatment for vitreous seeding. Enucleation is the treatment of choice for eyes with advanced disease.
摘要:
局部疗法越来越多地用于视网膜母细胞瘤的眼部保存。在中等收入国家,这些技术带来了特定的挑战,主要与诊断时更晚期的疾病有关.美国LatinadeOncologoíaPediátrica(GALOP)为视网膜母细胞瘤的保守治疗的管理制定了共识文件。动脉内化疗(OAC)是首选疗法,除了那些不太晚期疾病或年龄小于6个月的人。OAC允许在我们的环境中减少使用外部束放射治疗。玻璃体内化疗是玻璃体播种的首选治疗方法。眼球摘除是治疗晚期疾病的首选方法。
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