Abstract：
The guidelines for the implementation and reporting of HLA nomenclature for the World Marrow Donor Association have served as a reliable standard for communication of HLA data in the hematopoietic cell transplantation process. Wider use of next-generation sequencing made a special provision of the guidelines increasingly pertinent: how to communicate novel HLA alleles. Novel alleles need to be recognized by the WHO Nomenclature Committee for Factors of the HLA system to obtain official allele designations. Until then they have to be handled according to the specific rules. Leaving the actual rules basically unchanged we give some advice on how to communicate novel alleles to best facilitate the search process for cases where novel alleles are identified on donor or patient side.
摘要：
世界骨髓捐献者协会实施和报告HLA命名法的指南已成为造血细胞移植过程中HLA数据交流的可靠标准。下一代测序的广泛使用使指南的特殊规定越来越相关：如何传达新的HLA等位基因。新的等位基因需要由WHOHLA系统因子命名委员会认可才能获得正式的等位基因名称。在此之前，必须根据特定规则进行处理。在保持实际规则基本不变的情况下，我们就如何传达新等位基因提供了一些建议，以最好地促进在供体或患者侧识别新等位基因的情况下的搜索过程。
