Abstract：
This study aimed to explore the efficacy of single and combined effects of exercise and branched-chain amino acid (BCAA) supplements on improving frailty and quality of life in older adults. In total, 120 study participants were allocated into a combined exercise-and-BCAA supplementation group, an exercise-only group, a BCAA supplementation-only group, and a control group. Results showed that Fried\'s frailty score significantly decreased in the combined exercise-and-BCAA supplementation group (β= -1.73, p<0.001), exercise-only group (β= -1.68, p<0.001), and BCAA supplementation-only group (β= -0.73, p=0.005) compared to the control group. Moreover, the combination of exercise and BCAA supplements and the exercise-only program produced significant improvements in frailty compared to the BCAA supplement-only group and control group (p<0.05). Exercise should be a critical approach for older adults to improve frailty. Healthcare professionals in geriatric care should incorporate exercise programs as frailty management and prevention for older adults.
摘要：
这项研究旨在探讨运动和支链氨基酸（BCAA）补充剂的单一和联合作用对改善老年人的虚弱和生活质量的功效。总的来说,120名研究参与者被分配到运动和BCAA补充联合组，一个只锻炼的小组，仅补充BCAA组，和一个对照组。结果表明，运动和BCAA联合补充组Fried的虚弱评分显着降低（β=-1.73，p<0.001），仅运动组（β=-1.68，p<0.001），与对照组相比，仅补充BCAA组（β=-0.73，p=0.005）。此外，与仅BCAA补充剂组和对照组相比，运动和BCAA补充剂的组合以及仅运动计划在虚弱方面产生了显着改善（p<0.05）。锻炼应该是老年人改善虚弱的关键方法。老年护理专业人员应将运动计划纳入老年人的虚弱管理和预防。
