{Reference Type}: Journal Article {Title}: Community-based exercise and nutritional interventions to improve frailty syndrome among older adults: A quasi-experimental study. {Author}: Chen LF;Chang HC;Cai ZC;Chen YJ;Hsu WL;Chuang YH;Lee SC;Huang HC; {Journal}: Geriatr Nurs {Volume}: 51 {Issue}: 0 {Year}: May-Jun 2023 3 {Factor}: 2.525 {DOI}: 10.1016/j.gerinurse.2023.03.016 {Abstract}: This study aimed to explore the efficacy of single and combined effects of exercise and branched-chain amino acid (BCAA) supplements on improving frailty and quality of life in older adults. In total, 120 study participants were allocated into a combined exercise-and-BCAA supplementation group, an exercise-only group, a BCAA supplementation-only group, and a control group. Results showed that Fried's frailty score significantly decreased in the combined exercise-and-BCAA supplementation group (β= -1.73, p<0.001), exercise-only group (β= -1.68, p<0.001), and BCAA supplementation-only group (β= -0.73, p=0.005) compared to the control group. Moreover, the combination of exercise and BCAA supplements and the exercise-only program produced significant improvements in frailty compared to the BCAA supplement-only group and control group (p<0.05). Exercise should be a critical approach for older adults to improve frailty. Healthcare professionals in geriatric care should incorporate exercise programs as frailty management and prevention for older adults.