PDF(Pubmed)
Abstract：
UNASSIGNED: The DMagic trial showed that participatory learning and action (PLA) community mobilisation delivered through facilitated community groups, and mHealth voice messaging interventions improved diabetes knowledge in Bangladesh and the PLA intervention reduced diabetes occurrence. We assess intervention effects three years after intervention activities stopped.
UNASSIGNED: Five years post-randomisation, we conducted a cross-sectional survey among a random sample of adults aged ≥30-years living in the 96 DMagic villages, and a cohort of individuals identified with intermediate hyperglycaemia at the start of the DMagic trial in 2016. Primary outcomes were: 1) the combined prevalence of intermediate hyperglycaemia and diabetes; 2) five-year cumulative incidence of diabetes among the 2016 cohort of individuals with intermediate hyperglycaemia. Secondary outcomes were: weight, BMI, waist and hip circumferences, blood pressure, knowledge and behaviours. Primary analysis compared outcomes at the cluster level between intervention arms relative to control.
UNASSIGNED: Data were gathered from 1623 (82%) of the randomly selected adults and 1817 (87%) of the intermediate hyperglycaemia cohort. 2018 improvements in diabetes knowledge in mHealth clusters were no longer observable in 2021. Knowledge remains significantly higher in PLA clusters relative to control but no difference in primary outcomes of intermediate hyperglycaemia and diabetes prevalence (OR (95%CI) 1.23 (0.89, 1.70)) or five-year incidence of diabetes were observed (1.04 (0.78, 1.40)). Hypertension (0.73 (0.54, 0.97)) and hypertension control (2.77 (1.34, 5.75)) were improved in PLA clusters relative to control.
UNASSIGNED: PLA intervention effect on intermediate hyperglycaemia and diabetes was not sustained at 3 years after intervention end, but benefits in terms of blood pressure reduction were observed.
UNASSIGNED: Medical Research Council UK: MR/M016501/1 (DMagic trial); MR/T023562/1 (DClare study), under the Global Alliance for Chronic Diseases (GACD) Diabetes and Scale-up Programmes, respectively.
UNASSIGNED: Five years post-randomisation, we conducted a cross-sectional survey among a random sample of adults aged ≥30-years living in the 96 DMagic villages, and a cohort of individuals identified with intermediate hyperglycaemia at the start of the DMagic trial in 2016. Primary outcomes were: 1) the combined prevalence of intermediate hyperglycaemia and diabetes; 2) five-year cumulative incidence of diabetes among the 2016 cohort of individuals with intermediate hyperglycaemia. Secondary outcomes were: weight, BMI, waist and hip circumferences, blood pressure, knowledge and behaviours. Primary analysis compared outcomes at the cluster level between intervention arms relative to control.
UNASSIGNED: Data were gathered from 1623 (82%) of the randomly selected adults and 1817 (87%) of the intermediate hyperglycaemia cohort. 2018 improvements in diabetes knowledge in mHealth clusters were no longer observable in 2021. Knowledge remains significantly higher in PLA clusters relative to control but no difference in primary outcomes of intermediate hyperglycaemia and diabetes prevalence (OR (95%CI) 1.23 (0.89, 1.70)) or five-year incidence of diabetes were observed (1.04 (0.78, 1.40)). Hypertension (0.73 (0.54, 0.97)) and hypertension control (2.77 (1.34, 5.75)) were improved in PLA clusters relative to control.
UNASSIGNED: PLA intervention effect on intermediate hyperglycaemia and diabetes was not sustained at 3 years after intervention end, but benefits in terms of blood pressure reduction were observed.
UNASSIGNED: Medical Research Council UK: MR/M016501/1 (DMagic trial); MR/T023562/1 (DClare study), under the Global Alliance for Chronic Diseases (GACD) Diabetes and Scale-up Programmes, respectively.
摘要：
UNASSIGNED：DMagic试验表明，参与式学习和行动（PLA）社区动员是通过促进社区团体进行的，和mHealth语音信息干预改善了孟加拉国的糖尿病知识，解放军干预减少了糖尿病的发生。我们在干预活动停止三年后评估干预效果。
未经评估：随机化后五年，我们对居住在96个DMagic村庄的30岁以上的成年人进行了横断面调查，和一组在2016年DMagic试验开始时确定为中度高血糖的个体。主要结果是：1）中度高血糖和糖尿病的合并患病率；2）2016年中度高血糖患者队列中糖尿病的五年累积发病率。次要结果是：体重，BMI,腰围和臀围，血压,知识和行为。初步分析比较了干预组与对照组之间集群水平的结果。
UNASSIGNED：数据来自随机选择的1623名成年人（82％）和中度高血糖队列的1817名（87％）。2018年mHealth集群中糖尿病知识的改善在2021年不再可见。与对照组相比，PLA集群中的知识仍然明显更高，但在中间高血糖和糖尿病患病率（OR（95CI）1.23（0.89，1.70））或糖尿病五年发病率（1.04（0.78，1.40））的主要结局中没有差异。与对照组相比，PLA集群中的高血压（0.73（0.54，0.97））和高血压控制（2.77（1.34，5.75））得到了改善。
UNASSIGNED：PLA对中度高血糖和糖尿病的干预效果在干预结束后3年未持续，但观察到血压降低方面的益处。
UNASSIGNED：英国医学研究委员会：MR/M016501/1（DMagic试验）；MR/T023562/1（DClare研究），在全球慢性病联盟（GACD）糖尿病和扩大计划下，分别。
未经评估：随机化后五年，我们对居住在96个DMagic村庄的30岁以上的成年人进行了横断面调查，和一组在2016年DMagic试验开始时确定为中度高血糖的个体。主要结果是：1）中度高血糖和糖尿病的合并患病率；2）2016年中度高血糖患者队列中糖尿病的五年累积发病率。次要结果是：体重，BMI,腰围和臀围，血压,知识和行为。初步分析比较了干预组与对照组之间集群水平的结果。
UNASSIGNED：数据来自随机选择的1623名成年人（82％）和中度高血糖队列的1817名（87％）。2018年mHealth集群中糖尿病知识的改善在2021年不再可见。与对照组相比，PLA集群中的知识仍然明显更高，但在中间高血糖和糖尿病患病率（OR（95CI）1.23（0.89，1.70））或糖尿病五年发病率（1.04（0.78，1.40））的主要结局中没有差异。与对照组相比，PLA集群中的高血压（0.73（0.54，0.97））和高血压控制（2.77（1.34，5.75））得到了改善。
UNASSIGNED：PLA对中度高血糖和糖尿病的干预效果在干预结束后3年未持续，但观察到血压降低方面的益处。
UNASSIGNED：英国医学研究委员会：MR/M016501/1（DMagic试验）；MR/T023562/1（DClare研究），在全球慢性病联盟（GACD）糖尿病和扩大计划下，分别。
